Results 91 to 100 of about 12,150 (200)

FMRI guided DTI at the grey-white matter interface : with application to a connectivity analysis of the default mode network in Urbach-Wiethe disease

, 2011
Includes abstract.Includes bibliographical references.The cerebral cortex is composed of a thin layer of Grey Matter (GM), functionally subdivided into discrete regions which are connected in a large scale network via White Matter (WM) tracts. With fMRI (
Baasch, Roland
core  

Optimization of Diffusion MRI With Consideration of the Signal Decay in Biological Tissues

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 460-468, July 2026.
ABSTRACT Purpose Devising methodology to characterize and optimize acquisition schemes for biological tissues, such as the prostate, that produce model‐based synthetic diffusion‐weighted images and derived model parameters with predictable SNR improvement. Methods The averaging effect (AE) in synthetic diffusion‐weighted images obtained through fitting
Stefan Kuczera, Stephan E. Maier
wiley   +1 more source

Dipolar Order Mapping Based on Spin‐Lock Magnetic Resonance Imaging

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
To quantify the dipolar order relaxation time T1D$$ {T}_{1D} $$ using spin‐lock MRI technique, we introduce a T1D$$ {T}_{1D} $$‐specific ratio, denoted as RATIOdosl$$ {RATIO}_{dosl} $$. A novel rotary‐echo spin‐lock sequence was developed to enable dual‐frequency spin‐lock acquisition.
Zijian Gao, Qianxue Shan, Ziqin Zhou, Ziqiang Yu, Weitian Chen   +4 more
wiley   +1 more source

The effects of hypercapnia on DTI quantification in anesthetized rat brain [PDF]

, 2009
Diffusion Tensor Imaging (DTI) offers a valuable in vivo tool to characterize water diffusion behavior in biological tissues, particularly brain tissues.
E.X. Wu, Ding, AY, E.S. Hui, Hui, ES, Wu, EX, A.Y. Ding   +5 more
core   +1 more source

Operationalizing diffusion magnetic resonance imaging positivity for detection of vascular contributions to impairment and dementia

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION White matter lesions on fluid‐attenuated inversion recovery magnetic resonance imaging (FLAIR‐MRI) reflect small vessel disease (SVD) and aid in identifying vascular contributions to impairment and dementia (VCID). Emerging diffusion MRI (dMRI) biomarkers are sensitive to early SVD but the lack of validated approaches for defining
Mingzhao Hu, Scott A. Przybelski, Terry M. Therneau, Emily S. Lundt, Heather J. Wiste, Carly T. Mester, Michael Kamykowski, Robert I. Reid, Mary M. Machulda, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr., Jonathan Graff‐Radford, Prashanthi Vemuri   +13 more
wiley   +1 more source

Cognitive reserve against vascular contributions to cognitive impairment and dementia: A scoping review

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Vascular contributions to cognitive impairment and dementia (VCID) are common in older adults and are typically associated with cerebral small vessel disease (cSVD). However, little remains known about non‐pharmacological, modifiable lifestyle variables that may build cognitive reserve against cSVD/VCID.
Christopher E. Bauer, Colleen Pappas, Brian T. Gold   +2 more
wiley   +1 more source

DTI-015 Produces Cures in T9 Gliosarcoma

, 2003
DTI-015 (BCNU in 100% ethanol) utilizes solventfacilitated perfusion for the intratumoral treatment of gliomas. The water-miscible organic solvent vehicle, ethanol, facilitates a rapid and thorough saturation of the tumor with the dissolved anticancer ...
Frank Dmovsky, Ransohoff, Joseph, Pietronigro, Dennis, Joseph Ransohoff, Humberto Cravioto, Cravioto, Humberto, Dmovsky, Frank, Dennis Pietronigro   +7 more
core   +1 more source

Glymphatic dysfunction as an imaging biomarker for cognitive impairment in patients with β-thalassemia major: A multimodal MRI study

European Journal of Radiology Open
Background and purpose: Cerebral lymphatic abnormalities have been associated with neurodegenerative processes. However, brain glymphatic system and its role in cognitive impairment in β-thalassemia major (β-TM) remain unknown.
Xingye Yang, Meiru Bu, Xi Deng, Haifeng Zheng, Chengli Wu, Wei Cui, Muliang Jiang, Bihong T. Chen   +7 more
doaj   +1 more source

Choroid plexus remodeling linked to impaired CSF‐mediated clearance and Alzheimer's disease progression

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Impaired cerebrospinal fluid (CSF) ‐mediated clearance has been implicated in Alzheimer's disease (AD), but how choroid plexus (ChP) remodeling relates to these processes in vivo remains incompletely understood. METHODS In a large ADNI cohort, we integrated structural magnetic resonance imaging (MRI), amyloid/tau positron emission
Haolin Yin, Yuepeng Deng, ZiHao Lu, Yu Jiang, Chao Zuo, Jianyu Li, Linlin Guo, Binwu Ying, Giuseppe Battaglia, Xiaohe Tian, Qiyong Gong, for the Alzheimer's Disease Neuroimaging Initiative (ADNI)   +11 more
wiley   +1 more source

CYP46A1‐Targeted Treatment Alleviates Long‐Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Our findings demonstrate that CYP46A1 plays a critical role in regulating cholesterol homeostasis in microglia and that the targeting of CYP46A1 may offer a viable therapeutic approach for traumatic brain injury (TBI). The CYP46A1 activator Efavirenz reduces white matter damage by increasing the levels of the cholesterol metabolite 24OHC, thereby ...
Lin Li, You Shi, Qing Luo, Peiwen Guo, Taotao Jin, Xufang Ru, Zhouyang Jiang, Yin Niu, Wenyan Li, Yujie Chen, Zhi Chen   +10 more
wiley   +1 more source