Results 81 to 90 of about 10,072 (149)

Standard Model Imaging in the Brain and Spinal Cord of MS Patients: Initial Assessment and Comparison to Diffusion Tensor Imaging

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt, Alicia E. Cronin, Bailey Busher, Isabella Stuart, Grace Sweeney, Kristin P. O'Grady, Seth A. Smith, Samantha By, Kurt Schilling   +8 more
wiley   +1 more source

Effects of Physical Activity on Brain White Matter Integrity Are Region‐, Dose‐, and Age‐Dependent: Findings From the Population‐Based Rhineland Study

Aging Cell, Volume 25, Issue 8, August 2026.
Physical activity is related to more aligned white matter fibers and microstructural reorganization of the brain. Body weight, cardiometabolic, and inflammatory factors could partly mediate the effects of physical activity on brain white matter microstructure. The effects of physical activity on the brain are age‐ and region‐specific.
Eva Saxler, Fabienne A. U. Fox, Alexandra Koch, Xingwang Yang, Weiyi Zeng, Santiago Estrada, Monique M. B. Breteler, N. Ahmad Aziz   +7 more
wiley   +1 more source

Glymphatic dysfunction as an imaging biomarker for cognitive impairment in patients with β-thalassemia major: A multimodal MRI study

European Journal of Radiology Open
Background and purpose: Cerebral lymphatic abnormalities have been associated with neurodegenerative processes. However, brain glymphatic system and its role in cognitive impairment in β-thalassemia major (β-TM) remain unknown.
Xingye Yang, Meiru Bu, Xi Deng, Haifeng Zheng, Chengli Wu, Wei Cui, Muliang Jiang, Bihong T. Chen   +7 more
doaj   +1 more source

Comparison of two different analysis approaches for DTI free-water corrected and uncorrected maps in the study of white matter microstructural integrity in individuals with depression.

Human brain mapping, 2018
Diffusion tensor imaging (DTI) has often been used to examine white matter (WM) tract abnormalities in depressed subjects, but these studies have yielded inconsistent results, probably, due to gender composition or small sample size. In this study, we applied different analysis pipelines to a relatively large sample of individuals with depression to ...
Maurizio, Bergamino, Rayus, Kuplicki, Teresa A, Victor, Yoon-Hee, Cha, Martin P, Paulus   +4 more
openaire   +1 more source

Multi‐Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7416-7429, August 2026.
ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim, Salma Qassin, Lucy McKenna, Emma Hornsey, Dominic Italiano, Leonid Churilov, Richard J. MacIsaac, Jas‐mine Seah, Elif I. Ekinci, The Austin EMPA‐MRI Study Group   +9 more
wiley   +1 more source

Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
C57BL/6J and DBA/2J mice were used to investigate strain and sex‐specific features of the brain connectome in awake animals using magnetic resonance imaging (MRI). By combining resting‐state and diffusion MRI, we found significant differences in the motor, sensory, limbic, and salience networks between C57BL/6J and DBA/2J mice.
Tanzil M. Arefin, Hayreddin Said Ünsal, Thomas Neuberger, Nanyin Zhang, Helen M. Kamens   +4 more
wiley   +1 more source

Associations between glymphatic dysfunction, white matter injury, and cognitive decline in Parkinson’s disease

NeuroImage
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms, with cognitive impairment significantly affecting patients’ quality of life.
Jun Yao, Yuting Xia, Song’an Shang, Ting Huang, Youyong Tian, Wei Gao, Yan Gu, Yu-Chen Chen   +7 more
doaj   +1 more source

Glymphatic dysfunction in trigeminal neuralgia: A multimodal MRI study

Neurobiology of Disease
Background: Trigeminal neuralgia (TN) has traditionally been attributed to peripheral neurovascular compression at the trigeminal nerve root entry zone. Recent evidence, however, suggests central mechanisms may contribute to disease pathogenesis.
Tiantian Chu, Fei Xiong, Feng Gao, Ye Tu
doaj   +1 more source

Biophysical Diffusion MRI Models Better Identify White Matter Tracts in Edema

Tomography
Background/Objectives: White matter (WM) tract detection is critical in the presurgical planning of tumor resection. However, standard-of-care imaging techniques including T1-weighted, T2-weighted, and Diffusion Tensor Imaging (DTI) often fail to ...
Isaac E. Prentiss, Sasha Hakhu, Jennapher Lingo VanGilder, Parvathy Hareesh, Andrew Hooyman, Jason Yalim, Justin Hines, Gabe LaFond, Edward Ofori, Leslie C. Baxter, Yuxiang Zhou, Leland S. Hu, Kurt G. Schilling, Scott C. Beeman   +13 more
doaj   +1 more source

Distinguishing Early from Late Mild Cognitive Impairment Using Magnetic Resonance Free-Water Diffusion Tensor Imaging

NeuroSci
Mild Cognitive Impairment (MCI) is a transitional stage between normal aging and Alzheimer’s disease. Differentiating early MCI (EMCI) from late MCI (LMCI) is crucial for early diagnosis and intervention.
Maurizio Bergamino, Molly M. McElvogue, Ashley M. Stokes, Alzheimer’s Disease Neuroimaging Initiative   +3 more
doaj   +1 more source