Results 81 to 90 of about 12,150 (200)

T2‐Weighted T1 Mapping and Automated Segmentation of CSF: Assessment of Solute Gradients in the Healthy Brain

Journal of Magnetic Resonance Imaging, Volume 64, Issue 1, Page 218-227, July 2026.
ABSTRACT Background Cerebrospinal fluid (CSF) serves as a medium for nutrient delivery and waste clearance. The T1 relaxation rate, R1, can be used to measure the concentration of intrinsic solutes and extrinsic contrast agents. Purpose To implement a method for R1 mapping and segmentation of CSF and to use this method to explore how R1 of CSF relates ...
Tryggve Holck Storås, Sofie Lysholm Lian, Ingrid Mossige, Jørgen Riseth, Siri Fløgstad Svensson, Grethe Løvland, Geir Ringstad, Kent‐André Mardal, Kyrre Eeg Emblem, Kaja Nordengen   +9 more
wiley   +1 more source

A new in silico model to precisely design focused ultrasound brain therapies

Medical Physics, Volume 53, Issue 7, July 2026.
Abstract Background Focused ultrasound (FUS) combined with microbubbles enables transient and noninvasive blood–brain barrier (BBB) opening, facilitating targeted drug delivery. However, accurate treatment planning remains difficult due to inter‐patient anatomical variability and the common assumption in simulations that brain tissues behave like water.
Allegra Conti, Marta Grossi, Patricia Cardoso De Andrade, Andrea Duggento, Nicola Toschi   +4 more
wiley   +1 more source

Diffusion MRI free water is a sensitive marker of age-related changes in the cingulum

, 2019
International audienceAbstract Diffusion MRI is extensively used to investigate changes in white matter microstructure. However, diffusion measures within white matter tissue can be affected by partial volume effects due to cerebrospinal fluid and white ...
Amieva, Hélène, Dartigues, Jean-François, Rheault, François, Helmer, Catherine, Descoteaux, Maxime, Allard, Michèle, Edde, Manon, Dilharreguy, Bixente, Catheline, Gwénaëlle, Theaud, Guillaume   +9 more
core   +1 more source

Sex Differences in Alzheimer's Disease Revealed by Free-Water Diffusion Tensor Imaging and Voxel-Based Morphometry. [PDF]

J Alzheimers Dis, 2022
Bergamino M, Keeling EG, Baxter LC, Sisco NJ, Walsh RR, Stokes AM.   +5 more
europepmc   +1 more source

Quantitative Diffusion and T2 Mapping Using RF‐Modulated Phase‐Based Gradient Echo Imaging

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 49-65, July 2026.
ABSTRACT Purpose To introduce and evaluate the feasibility of a novel RF‐phase modulated gradient echo (GRE) method for quantitative diffusion MRI, aimed at mitigating geometric distortion and enabling high‐resolution 3D quantitative diffusion/T2 mapping as a complementary alternative to conventional DWI.
Daiki Tamada, Ali Pirasteh, David F. Jarrard, Diego Hernando, Scott B. Reeder   +4 more
wiley   +1 more source

Clinically Feasible White Matter Fiber Tractography in Peritumoral Zones With Cerebral Vasogenic Edema

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 287-301, July 2026.
ABSTRACT Purpose In diffusion MRI, vasogenic edema manifests as a major fraction of isotropic water that dilutes the anisotropic intra‐axonal portion of the signal. Many tractography algorithms mistake vasogenic edema for the white matter boundary and terminate tracking to prevent producing spurious streamlines.
Patryk Filipiak, Timothy M. Shepherd, Kamri Clarke, Gaia Ressa, Dimitris G. Placantonakis, Fernando E. Boada, Steven H. Baete   +6 more
wiley   +1 more source

Identifying rodent olfactory bulb structures with micro-DTI [PDF]

, 2008
Olfactory bulb (OB) is one of the most developed systems in rodent models with complex neuronal organization and anatomical structures. MR diffusion tensor imaging (DTI) is a non-invasive technique to probe tissue microstructures by examining the ...
Chan, KC, K.C. Chan, E.X. Wu, P.T. Lai, E.S. Hui, Cai, KX, H. Guo, Zhao, XG, Lai, PT, Guo, H, X.G. Zhao, Hui, ES, K.X. Cai, Wu, EX   +13 more
core   +1 more source

Gray matter microstructure alterations with excess extra-cellular free water contribute to cognitive dysfunction in bipolar disorder: A comparative analysis with white matter pathology

NeuroImage
Background: Bipolar disorder (BD) is a chronic mental disorder involving cognitive dysfunction. Imaging studies reveal reduced cortical thickness and impaired white matter integrity in BD; however, the biological pathophysiology underlying cognitive ...
Yasuhito Nagai, Toshimasa Fujimura, Wataru Uchida, Rinako Iseki, Koji Kamagata, Shigeki Aoki, Tadafumi Kato   +6 more
doaj   +1 more source

White matter abnormalities in patients with focal cortical dysplasia revealed by diffusion tensor imaging (DTI) analysis in a voxelwise approach

Frontiers in Neurology, 2012
Background: Diffusion tensor imaging (DTI) allows the analysis of changes in microstructure, through the quantification of the spread and direction of water molecules in tissues.
Viviane Carvalho Fonseca, Clarissa Lin Yasuda, Guilherme Garlipp Tedeschi, Luiz Eduardo eBetting, Fernando eCendes   +4 more
doaj   +1 more source

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 349-365, July 2026.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps, Nyoman D. Kurniawan, Geoff Watson, Paul Sved, Samson Dowland, Eleftheria Panagiotaki, David Atkinson, Roger Bourne   +7 more
wiley   +1 more source