Scientific Reports, 2021 Magnetic resonance imaging (MRI) based diffusion tensor imaging (DTI) can assess white matter (WM) integrity through several metrics, such as fractional anisotropy (FA), axial/radial diffusivities (AxD/RD), and mode of anisotropy (MA).
Maurizio Bergamino +2 more
doaj +2 more sources
Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia
, 2017 Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the as-sumption of a Gaussian distribution of diffusion in neu-ral architecture.
Colgan, Niall +5 more
openaire +3 more sources
Neuro-OncologyAbstract Background Glioblastoma (GBM) may disrupt glymphatic function and neurofluid dynamics locally and in distant brain regions. However, the prognostic relevance of such alterations remains unclear.
Akifumi Hagiwara +2 more
exaly +5 more sources
White and gray matter diffusion-derived differences in type 2 diabetes mellitus: a free-water-corrected diffusion MRI study [PDF]
Frontiers in MedicineBackgroundType 2 diabetes mellitus (T2DM) is frequently accompanied by complex brain microstructural abnormalities and cognitive decline. Conventional diffusion tensor imaging (DTI) metrics can reflect both tissue diffusion properties and extracellular ...
Dandan Lin +7 more
doaj +2 more sources
Multimodal diffusion MRI biomarkers of white matter alterations and clinical impairment in mTBI [PDF]
Frontiers in NeuroscienceIntroductionMild traumatic brain injury (mTBI), which includes concussion, often results in subtle white matter abnormalities that are not detectable with conventional neuroimaging.
Maurizio Bergamino +5 more
doaj +2 more sources
NeuroradiologyAbstract Purpose Diffusion MRI–based indirect indices of neurofluid dynamics, such as diffusion tensor imaging along the perivascular space (DTI-ALPS) and extracellular free water (FW), have been reported to have prognostic implications in glioblastoma.
Seung Hong Choi +2 more
exaly +3 more sources
Characterizing Peritumoral Tissue Using Free Water Elimination in Clinical DTI
, 2018 Finding an accurate microstructural characterization of the peritumoral region is essential to distinguish between edema and infiltration, enabling the distinction between tumor types, and to improve tractography in this region. Characterization of healthy versus pathological tissue is a key concern when modeling tissue microstructure in the ...
Ould Ismail, Abdol Aziz +7 more
core +3 more sources
Advanced diffusion MRI tract signatures in Alzheimer’s disease, dementia with Lewy bodies, and the FTD/PPA spectrum [PDF]
NeuroImageAlzheimer’s disease (AD), Dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), and primary progressive aphasia (PPA) are heterogeneous neurodegenerative syndromes with overlapping clinical features and substantial societal burden.
Yuqi Tian, Jennifer L. Whitwell
doaj +2 more sources
Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging. [PDF]
PLoS ONE, 2017 Brain changes associated with Alzheimer's disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD, neuronal loss and synaptic pathology are closely related to the cognitive ...
Andrew R Hoy +10 more
doaj +3 more sources
Amyloid-beta statuses prediction with free water MR imaging features in Alzheimer’s disease using machine learning models [PDF]
BMC Medical ImagingPurpose This study aimed to identify the effectiveness of free water MRI (FW-MRI) features for predicting amyloid-beta (Aβ) statuses in Alzheimer’s disease (AD) by constructing diagnostic models using machine learning analysis.
Rongshen Zhou +14 more
doaj +2 more sources