Results 21 to 30 of about 10,072 (149)

Free-water diffusion tensor imaging detects occult periependymal abnormality in the AQP4-IgG-seropositive neuromyelitis optica spectrum disorder

Scientific Reports, 2022
To compare free-water corrected diffusion tensor imaging (DTI) measures in the normal-appearing periependymal area between AQP4-IgG-seropositive NMOSD and multiple sclerosis (MS) to investigate occult pathophysiology.
Minchul Kim, Kyu Sung Choi, Ryoo Chang Hyun, Inpyeong Hwang, Tae Jin Yun, Sung Min Kim, Ji-hoon Kim   +6 more
doaj   +1 more source

Multi-compartment diffusion magnetic resonance imaging models link tract-related characteristics with working memory performance in healthy older adults

Frontiers in Aging Neuroscience, 2022
Multi-compartment diffusion MRI metrics [such as metrics from free water elimination diffusion tensor imaging (FWE-DTI) and neurite orientation dispersion and density imaging (NODDI)] may reflect more specific underlying white-matter tract ...
Christopher E. Bauer, Valentinos Zachariou, Pauline Maillard, Pauline Maillard, Arvind Caprihan, Brian T. Gold, Brian T. Gold   +6 more
doaj   +1 more source

Diffusion magnetic resonance imaging-based surrogate marker in amyotrophic lateral sclerosis

Exploration of Neuroprotective Therapy, 2023
Amyotrophic lateral sclerosis (ALS) is the most prevalent type of motor neuron disease (MND) and is diagnosed with a delay from the first appearance of symptoms.
Yuya Saito
doaj   +1 more source

Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer’s disease with and without cerebrovascular disease

Alzheimer’s Research & Therapy, 2017
Background Mixed vascular and neurodegenerative dementia, such as Alzheimer’s disease (AD) with concomitant cerebrovascular disease, has emerged as the leading cause of age-related cognitive impairment. The brain white matter (WM) microstructural changes
Fang Ji, Ofer Pasternak, Siwei Liu, Yng Miin Loke, Boon Linn Choo, Saima Hilal, Xin Xu, Mohammad Kamran Ikram, Narayanaswamy Venketasubramanian, Christopher Li-Hsian Chen, Juan Zhou   +10 more
doaj   +1 more source

White matter and nigral alterations in multiple system atrophy-parkinsonian type

npj Parkinson's Disease, 2021
Multiple system atrophy (MSA) is classified into two main types: parkinsonian and cerebellar ataxia with oligodendrogliopathy. We examined microstructural alterations in the white matter and the substantia nigra pars compacta (SNc) of patients with MSA ...
Takashi Ogawa, Taku Hatano, Koji Kamagata, Christina Andica, Haruka Takeshige-Amano, Wataru Uchida, Daiki Kamiyama, Yasushi Shimo, Genko Oyama, Atsushi Umemura, Hirokazu Iwamuro, Masanobu Ito, Masaaki Hori, Shigeki Aoki, Nobutaka Hattori   +14 more
doaj   +1 more source

High-fidelity diffusion tensor imaging of the cervical spinal cord using point-spread-function encoded EPI

NeuroImage, 2021
Diffusion tensor imaging (DTI) of the spinal cord is technically challenging due to the size of its structure and susceptibility-induced field inhomogeneity, which impedes clinical applications.
Sisi Li, Yishi Wang, Zhangxuan Hu, Li Guan, Yong Hai, Hanwen Zhang, Le He, Wen Jiang, Hua Guo   +8 more
doaj   +1 more source

Free water: A marker of age-related modifications of the cingulum white matter and its association with cognitive decline.

PLoS ONE, 2020
Diffusion MRI is extensively used to investigate changes in white matter microstructure. However, diffusion measures within white matter tissue can be affected by partial volume effects due to cerebrospinal fluid and white matter hyperintensities ...
Manon Edde, Guillaume Theaud, François Rheault, Bixente Dilharreguy, Catherine Helmer, Jean-François Dartigues, Hélène Amieva, Michèle Allard, Maxime Descoteaux, Gwénaëlle Catheline   +9 more
doaj   +1 more source

Distinct tumor signatures using deep learning-based characterization of the peritumoral microenvironment in glioblastomas and brain metastases

Scientific Reports, 2021
Tumor types are classically distinguished based on biopsies of the tumor itself, as well as a radiological interpretation using diverse MRI modalities.
Zahra Riahi Samani, Drew Parker, Ronald Wolf, Wes Hodges, Steven Brem, Ragini Verma   +5 more
doaj   +1 more source

Diffusion tensor free water MRI predicts progression of FLAIR white matter hyperintensities after ischemic stroke

Frontiers in Neurology, 2023
BackgroundThe progression of FLAIR white matter hyperintensities (WMHs) on MRI heralds vascular-mediated cognitive decline. Even before FLAIR WMH progression, adjacent normal appearing white matter (NAWM) already demonstrates microstructural ...
Kyle C. Kern, Marwah S. Zagzoug, Rebecca F. Gottesman, Clinton B. Wright, Richard Leigh, Richard Leigh   +5 more
doaj   +1 more source

Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia

, 2017
Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the as-sumption of a Gaussian distribution of diffusion in neu-ral architecture.
Colgan, Niall, O'Reilly, David, Holleran, Laurena, Ahmed, Mohamed, McDonald, Colm, Cannon, Dara M.   +5 more
openaire   +2 more sources