Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson's disease [PDF]
BACKGROUND: Free-water imaging can predict and monitor dopamine system degeneration in people with Parkinson's disease. It can also enhance the sensitivity of traditional diffusion tensor imaging (DTI) metrics for indexing neurodegeneration.
Lord, Sue +15 more
core +2 more sources
Corrigendum to: Contralateral neurofluid dynamics predict survival in IDH wild-type glioblastoma: A DTI-ALPS and free water imaging study. [PDF]
europepmc +2 more sources
Comparison of two different analysis approaches for DTI free-water corrected and uncorrected maps in the study of white matter microstructural integrity in individuals with depression [PDF]
Maurizio Bergamino +2 more
exaly +2 more sources
Free‐water DTI estimates from single b‐value data might seem plausible but must be interpreted with care [PDF]
PurposeFree‐water elimination DTI (FWE‐DTI) has been used widely to distinguish increases of free‐water partial‐volume effects from tissue’s diffusion in healthy aging and degenerative diseases. Because the FWE‐DTI fitting is only well‐posed for multishell acquisitions, a regularized gradient descent (RGD) method was proposed to enable application to ...
Marc Golub +2 more
openaire +3 more sources
To compare free-water corrected diffusion tensor imaging (DTI) measures in the normal-appearing periependymal area between AQP4-IgG-seropositive NMOSD and multiple sclerosis (MS) to investigate occult pathophysiology.
Minchul Kim +6 more
doaj +1 more source
Multi-compartment diffusion MRI metrics [such as metrics from free water elimination diffusion tensor imaging (FWE-DTI) and neurite orientation dispersion and density imaging (NODDI)] may reflect more specific underlying white-matter tract ...
Christopher E. Bauer +6 more
doaj +1 more source
Diffusion magnetic resonance imaging-based surrogate marker in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is the most prevalent type of motor neuron disease (MND) and is diagnosed with a delay from the first appearance of symptoms.
Yuya Saito
doaj +1 more source
Background Mixed vascular and neurodegenerative dementia, such as Alzheimer’s disease (AD) with concomitant cerebrovascular disease, has emerged as the leading cause of age-related cognitive impairment. The brain white matter (WM) microstructural changes
Fang Ji +10 more
doaj +1 more source
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis : a pilot project of the ENIGMA–DTI working group [PDF]
The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was set up to analyze brain measures and genotypes from multiple sites across the world to improve the power to detect genetic variants that influence the brain.
Sprooten, Emma +63 more
core +1 more source
White matter and nigral alterations in multiple system atrophy-parkinsonian type
Multiple system atrophy (MSA) is classified into two main types: parkinsonian and cerebellar ataxia with oligodendrogliopathy. We examined microstructural alterations in the white matter and the substantia nigra pars compacta (SNc) of patients with MSA ...
Takashi Ogawa +14 more
doaj +1 more source

