Results 31 to 40 of about 8,572,069 (168)

White matter and nigral alterations in multiple system atrophy-parkinsonian type

npj Parkinson's Disease, 2021
Multiple system atrophy (MSA) is classified into two main types: parkinsonian and cerebellar ataxia with oligodendrogliopathy. We examined microstructural alterations in the white matter and the substantia nigra pars compacta (SNc) of patients with MSA ...
Takashi Ogawa, Taku Hatano, Koji Kamagata, Christina Andica, Haruka Takeshige-Amano, Wataru Uchida, Daiki Kamiyama, Yasushi Shimo, Genko Oyama, Atsushi Umemura, Hirokazu Iwamuro, Masanobu Ito, Masaaki Hori, Shigeki Aoki, Nobutaka Hattori   +14 more
doaj   +1 more source

High-fidelity diffusion tensor imaging of the cervical spinal cord using point-spread-function encoded EPI

NeuroImage, 2021
Diffusion tensor imaging (DTI) of the spinal cord is technically challenging due to the size of its structure and susceptibility-induced field inhomogeneity, which impedes clinical applications.
Sisi Li, Yishi Wang, Zhangxuan Hu, Li Guan, Yong Hai, Hanwen Zhang, Le He, Wen Jiang, Hua Guo   +8 more
doaj   +1 more source

Comparison of two different analysis approaches for DTI free-water corrected and uncorrected maps in the study of white matter microstructural integrity in individuals with depression [PDF]

Human Brain Mapping, 2017
Diffusion tensor imaging (DTI) has often been used to examine white matter (WM) tract abnormalities in depressed subjects, but these studies have yielded inconsistent results, probably, due to gender composition or small sample size. In this study, we applied different analysis pipelines to a relatively large sample of individuals with depression to ...
Maurizio Bergamino, Rayus Kuplicki, Teresa A. Victor, Yoon-Hee Cha, Martin P. Paulus   +4 more
openaire   +2 more sources

Distinct tumor signatures using deep learning-based characterization of the peritumoral microenvironment in glioblastomas and brain metastases

Scientific Reports, 2021
Tumor types are classically distinguished based on biopsies of the tumor itself, as well as a radiological interpretation using diverse MRI modalities.
Zahra Riahi Samani, Drew Parker, Ronald Wolf, Wes Hodges, Steven Brem, Ragini Verma   +5 more
doaj   +1 more source

Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson’s disease [PDF]

Background: Free-water imaging can predict and monitor dopamine system degeneration in people with Parkinson’s disease. It can also enhance the sensitivity of traditional diffusion tensor imaging (DTI) metrics for indexing neurodegeneration.
Duncan GW, Khoo TK, Galna B, Martin SL, Sigurdsson HP, Lord S, Bergamino M, Wilson J, Ray NH, Lawson RA, Alcock L, Burn DJ, Rea R, Rochester L, Taylor JP, O'Brien JT, Yarnall AJ   +16 more
core   +3 more sources

Diffusion tensor free water MRI predicts progression of FLAIR white matter hyperintensities after ischemic stroke

Frontiers in Neurology, 2023
BackgroundThe progression of FLAIR white matter hyperintensities (WMHs) on MRI heralds vascular-mediated cognitive decline. Even before FLAIR WMH progression, adjacent normal appearing white matter (NAWM) already demonstrates microstructural ...
Kyle C. Kern, Marwah S. Zagzoug, Rebecca F. Gottesman, Clinton B. Wright, Richard Leigh, Richard Leigh   +5 more
doaj   +1 more source

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis : a pilot project of the ENIGMA–DTI working group [PDF]

, 2013
The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was set up to analyze brain measures and genotypes from multiple sites across the world to improve the power to detect genetic variants that influence the brain.
Sprooten, Emma, Glahn, David C., Curran, Joanne E., Mandl, R.C., Almasy, L., Kochunov, Peter V., Hulshoff Pol, H.E., Curran, J.E., Starr, John M., Brouwer, Rachel M., Wardlaw, J.M., Mitchell, Braxton D., Brouwer, R.M., Wright, M.J., Bastin, M.E., Mandl, René C., Medland, Sarah E., Glahn, D.C., Sussmann, Jessika E., Medland, S.E., Martin, N.G., McMahon, K.L., Landman, Bennett A., Hulshoff Pol, Hilleke E., Nichols, T.E., Nichols, Thomas E., Toga, Arthur W., Peterson, C.P., Thompson, P.M., Jahanshad, N., Martin, Nicholas G., Wardlaw, Joanna M., Sprooten, E., Mitchell, B.D., McIntosh, A.M.; id_orcid, Pol, Hilleke E. Hulshoff, Hong, L. Elliot, Peterson, Charles P., Deary, Ian J., Hong, L.E., Kochunov, P.V., Jahanshad, Neda, Duggirala, Ravi, Bastin, Mark E., Fox, Peter T., McIntosh, Andrew M., de Zubicaray, G.I., de Zubicaray, Greig I., Landman, B.A., Fox, P.T., Thompson, Paul M., McMahon, Katie L., Blangero, J., Olvera, Rene L., Sussmann, J.E., Olvera, R.L., McIntosh, A.M., Wright, Margaret J., Duggirala, R., Almasy, Laura, Blangero, John, Starr, J.M., Toga, A.W., Deary, I.J.   +63 more
core   +2 more sources

Diffusion Bubble Model: A novel MRI approach for detection and subtyping of neonatal punctate white matter lesions

NeuroImage
Diffusion magnetic resonance imaging, particularly diffusion tensor imaging (DTI), is an indispensable non-invasive tool for visualizing brain structure and detecting injuries by tracking water molecule motion.
Erjun Zhang, Benjamin De Leener, Gregory A. Lodygensky   +2 more
doaj   +1 more source

New insights in addressing cerebral small vessel disease: Associated with extracellular fluid in white matter

Frontiers in Neuroscience, 2022
ObjectiveTo explore the role of extracellular fluid, assessed by diffusion tensor imaging (DTI) metrics of free water (FW), in the white matter of patients with cerebral small vessel disease (CSVD).Materials and methodsThe baseline clinical and imaging ...
Haiyuan Lan, Xinjun Lei, Zhihua Xu, Songkuan Chen, Wanfeng Gong, Yunqi Cai   +5 more
doaj   +1 more source

The evolution of white matter microstructural changes after mild traumatic brain injury: A longitudinal DTI and NODDI study [PDF]

, 2020
Neuroimaging biomarkers that can detect white matter (WM) pathology after mild traumatic brain injury (mTBI) and predict long-term outcome are needed to improve care and develop therapies.
Diaz-Arrastia, R, Vassar, MJ, Temkin, N, Palacios, EM, Giacino, JT, Okonkwo, DO, Robertson, CS, Jain, S, Stein, MB, MacDonald, CL, Mukherjee, P, Owen, JP, McCrea, M, Levin, HS, Yuh, EL, Manley, GT, Wang, MB, Ferguson, AR, Investigators, TRACK-TBI   +18 more
core   +1 more source