Results 31 to 40 of about 10,072 (149)

White matter abnormalities in amyotrophic lateral sclerosis: a free water imaging study

Frontiers in Neuroscience
ObjectiveTo investigate white matter microstructural alterations in amyotrophic lateral sclerosis (ALS) using free-water-corrected diffusion tensor imaging (FW-DTI), compare its findings with those of conventional DTI, and examine the clinical ...
Zelin Liu, Haiqing Yang, Jiawei Cui, Zhengkun Guan, Duo Gao, Pingyong Feng, He Yang, Wenyi Li, Yuanhui Zhao, Qianhang Yang, Xuyang Zheng, Qi Liu, Zuojun Geng, Zuojun Geng   +13 more
doaj   +1 more source

New insights in addressing cerebral small vessel disease: Associated with extracellular fluid in white matter

Frontiers in Neuroscience, 2022
ObjectiveTo explore the role of extracellular fluid, assessed by diffusion tensor imaging (DTI) metrics of free water (FW), in the white matter of patients with cerebral small vessel disease (CSVD).Materials and methodsThe baseline clinical and imaging ...
Haiyuan Lan, Xinjun Lei, Zhihua Xu, Songkuan Chen, Wanfeng Gong, Yunqi Cai   +5 more
doaj   +1 more source

Diffusion Bubble Model: A novel MRI approach for detection and subtyping of neonatal punctate white matter lesions

NeuroImage
Diffusion magnetic resonance imaging, particularly diffusion tensor imaging (DTI), is an indispensable non-invasive tool for visualizing brain structure and detecting injuries by tracking water molecule motion.
Erjun Zhang, Benjamin De Leener, Gregory A. Lodygensky   +2 more
doaj   +1 more source

Chloride Ions: Essential Agents for Achieving Spontaneous Delamination of MXene

Advanced Materials, EarlyView.
This work first identifies chloride ions as essential agents for spontaneous MXene delamination. Without Cl−, etched Ti3C2Tx remains multilayered; with Cl−, interlayer modification enables Li+ intercalation and osmotic swelling. The SPEED process couples HF‐assisted Al extraction, Cl−‐mediated interlayer expansion, and Li+‐driven swelling to produce ...
Sukhyeun Jang, Yong‐Jae Kim, Incheol Jeong, Minju Kim, Jaewoong Lee, Jihan Kim, Ki‐Min Roh, Kang Taek Lee, Seon Joon Kim, Yonghee Lee, Chi Won Ahn, Hee‐Tae Jung   +11 more
wiley   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Tissue-specific diffusion abnormalities and localized free-water reductions in hypertension despite no detectable group difference in the DTI-ALPS index

Frontiers in Medicine
BackgroundEssential hypertension (HTN) is an established risk factor for cerebral small vessel disease and cognitive decline. Although conventional diffusion tensor imaging (DTI) has identified white matter (WM) abnormalities in HTN, these metrics are ...
Taipeng Zeng, Taipeng Zeng, Xiaoyang Wang, Wenhui Xu, Zhifeng Huang, Hui Xiong, Kanlin Lin, Hao Huang, Jianfeng Chu, Shangwen Xu, Liyuan Fu   +10 more
doaj   +1 more source

DDSurfer: A Weakly‐Supervised Dual‐Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI

Advanced Science, EarlyView.
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li, Wei Zhang, Xi Zhu, Yuqian Chen, Nir A. Sochen, Jarrett Rushmore, Carl‐Fredrik Westin, Yogesh Rathi, Lauren J. O'Donnell, Ofer Pasternak, Fan Zhang   +10 more
wiley   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Diffusion MRI-based analysis of functional alterations of the glymphatic system in children with non-lesional epilepsy

NeuroImage: Reports
Objective: Based on diffusion tensor imaging (DTI) data, we used DTI-analysis along the perivascular space (DTI-ALPS) and free-water mapping to investigate the function of the glymphatic system and its relationship with clinical features among pediatric ...
Bixia Wu, Gengbiao Zhang, Yanting Wang, Hongyi Zheng, Hui Tan, Wenbin Zheng   +5 more
doaj   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

Anatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan, Rohini Punja, Thomas Iype, Chandrasekharan Kesavadas, Bejoy Thomas, Kannanvilakom Govindapillai Umesan, Aswathy Maria Oommen, Usha Devi Keezhathil Bhargavi   +7 more
wiley   +1 more source