Results 51 to 60 of about 8,572,069 (168)

Multi‐Parametric Phase‐Cycled Balanced Steady‐State Free Precession Brain Tissue Characterization in Relapsing‐Remitting Multiple Sclerosis

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Time‐efficient phase‐cycled balanced steady‐state free precession (pc‐bSSFP) imaging is a novel microstructure‐ and myelin‐sensitive approach for multi‐parametric brain tissue characterization not yet evaluated in demyelinating diseases such as multiple sclerosis (MS).
Florian Birk, Benjamin Bender, Hamzeh Tesh, Anagha Deshmane, Maris M. Fabian, Markus C. Kowarik, Tobias Lindig, Ulrike Ernemann, Klaus Scheffler, Rahel Heule   +9 more
wiley   +1 more source

Simplified Anisotropic IVIM Using Spherical Means and an Application in the Placenta

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To reduce the complexity associated with anisotropic IVIM modeling, we derived two simplified diffusion MRI models that map the apparent diffusivity, relative proportions, and anisotropy of perfusion‐ and diffusion‐related signal components and demonstrated them in placenta scans.
Paddy J. Slator, Luke Pleva, Alexandra Crawford, Lucy Higgins, Edward Johnstone, Alexander E. P. Heazell, Daniel C. Alexander, Josephine H. Naish, Kate Duhig   +8 more
wiley   +1 more source

A systematic review of DTI studies in Bipolar Disorder [PDF]

, 2012
Includes bibliographical references.In the last decade, multiple diffusion tensor imaging (DTI) studies have revealed changes in the microstructure of white matter in bipolar disorder.
Nortje, Gareth
core   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Muscle morphology and intramuscular fat after treatment‐as‐usual including botulinum neurotoxin A injections in children with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Normalized muscle volume remained unchanged in all evaluated muscles after the 12‐month treatment‐as‐usual in children with cerebral palsy. Higher intramuscular fat fraction was observed in the medial gastrocnemius, suggesting concurrent intramuscular fat infiltration.
Zhongzheng Wang, Antea Destro, Alexandra Åhblom, Sven Petersson, Ferdinand Von Walden, Eva Pontén, Cecilia Lidbeck, Ruoli Wang   +7 more
wiley   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Microstructure, length, and connection of limbic tracts in normal human brain development

Frontiers in Aging Neuroscience, 2014
The cingulum and fornix play an important role in memory, attention, spatial orientation and feeling functions. Both microstructure and length of these limbic tracts can be affected by mental disorders such as Alzheimer’s disease, depression, autism ...
Qiaowen eYu, Qiaowen eYu, Yun ePeng, Virendra eMishra, Austin eOuyang, Hang eLi, Hong eZhang, Min eChen, Shuwei eLiu, Hao eHuang, Hao eHuang   +10 more
doaj   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba, Caroline G. M. de Theije, Valentina Salvi, Dominique Viveen, Sebastiaan W. T. Corstjens, Marijke. E. J. Achterberg, Yohan van de Looij, Freek E. Hoebeek, Cora H. A. Nijboer   +8 more
wiley   +1 more source

Comparative Performance Analysis of an Open Source Motion‐Compensated Cardiac Diffusion Sequence Across Different MRI Systems and Gradient Strengths—A Pilot Study

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2629-2641, December 2026.
ABSTRACT Purpose To validate the performance of an open‐source cardiac diffusion sequence framework and to investigate hardware‐based performance differences. Methods Three second order motion compensated sequence files were compiled using Pulseq and applied across different MRI systems to image five volunteers.
Eric Arbes, Ariel Hannum, Johannes Fischer, Qingping Chen, Sebastian Littin, Alexander Maier, Michael Bock, Simon Reiss   +7 more
wiley   +1 more source