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Free Radicals

Neonatal Network, 2002
Free radicals may be the cause of many neonatal complications, such as chronic lung disease and brain injury. Treatment options for these complications using antioxidants are being evaluated through research. This article begins with a review of the basic science of free radicals.
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The wanderings of a free radical

Free Radical Biology and Medicine, 2009
In my career I have moved from chemistry to biochemistry to plant science to clinical chemistry and back again (in a partial way) to plants. This review presents a brief history of my research achievements (ascorbate-glutathione cycle, role of iron in oxidative damage and human disease, biomarkers of free radical damage, and studies on atherosclerosis ...
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Free Radicals in Toxicology

Toxicology and Applied Pharmacology, 1993
Free radicals are recognized more and more frequently as being involved in the mechanism of toxicity of chemicals. In some cases, the organic radicals are involved, but often oxygen radicals result from redox cycling chemicals. Free radicals are usually very reactive, which, in addition to causing toxicities, can make them difficult to detect. Electron
S D, Aust   +4 more
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Sunlight and free radicals

Nature Chemistry, 2013
Thomas Tidwell reflects on the overlooked — but prescient — proposal by the British chemists Arthur Downes and Thomas Blunt for photochemical free-radical formation, decades before Moses Gomberg launched the field of radical chemistry by preparing triphenylmethyl, the first stable organic radical.
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Free Radicals and Disease

Archives of Biochemistry and Biophysics, 2002
Free radicals and reactive oxygen species (ROS) have been associated with the etiology and/or progression of a number of diseases and in aging. Many of the proteins oxidatively modified by free radicals contain side-chain carbonyl derivatives, which can be used as markers for protein oxidation.
Jackob, Moskovitz   +2 more
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Free radicals in aging

Molecular and Cellular Biochemistry, 1988
Aging is the progressive accumulation of changes with time that are responsible for the ever-increasing likelihood of disease and death. These irreversible changes are attributed to the aging process. This process is now the major cause of death in the developed countries. This fact is obscured by the protean nature of the contributions of this process
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Apoptosis and Free Radicals

Annals of the New York Academy of Sciences, 1994
Necrotic cell death is usually a consequence of extensive insult to the cell, leading to release of intracellular contents and an inflammatory response. Apoptosis, however, is a physiological response to damaging influences that requires sufficient maintenance of homeostasis to allow execution of the pathway.
K A, Wood, R J, Youle
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AN APPROACH TO FREE RADICALS

The Lancet, 1983
Free radicals have become a buzz word in experimental pathology and they are beginning to impinge on clinical practice.
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Apoptosis and Free Radicals

Biochemical and Molecular Medicine, 1996
Free radicals that appear during physiological processes may lead to apoptosis in some pathological conditions when antioxidant capacity of the tissue is surpassed. Additionally, free radicals are involved in the control of apoptosis; antioxidant agents suppress apoptosis induced by a variety of stimuli.
I, Stoian, A, Oros, E, Moldoveanu
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