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The Contribution of Dietary Fructose to Non-alcoholic Fatty Liver Disease

open access: yesFrontiers in Pharmacology, 2021
Fructose, especially industrial fructose (sucrose and high fructose corn syrup) is commonly used in all kinds of beverages and processed foods. Liver is the primary organ for fructose metabolism, recent studies suggest that excessive fructose intake is a
Siyu Yu, Chunlin Li, Guang Ji, Li Zhang
doaj   +1 more source

Fructose Metabolism and Cardiac Metabolic Stress

open access: yesFrontiers in Pharmacology, 2021
Cardiovascular disease is one of the leading causes of mortality in diabetes. High fructose consumption has been linked with the development of diabetes and cardiovascular disease.
M. Annandale   +11 more
doaj   +1 more source

SGLT5 reabsorbs fructose in the kidney but its deficiency paradoxically exacerbates hepatic steatosis induced by fructose. [PDF]

open access: yesPLoS ONE, 2013
Although excessive fructose intake is epidemiologically linked with dyslipidemia, obesity, and diabetes, the mechanisms regulating plasma fructose are not well known.
Taku Fukuzawa   +13 more
doaj   +1 more source

Dietary fructose and its association with the metabolic syndrome in Lebanese healthy adults: a cross-sectional study

open access: yesDiabetology & Metabolic Syndrome, 2022
Background Epidemiological studies investigating the association between dietary fructose intake and the metabolic syndrome (MetS) are scarce and have produced controversial findings.
Rita Aoun   +6 more
doaj   +1 more source

Evolving a New Efficient Mode of Fructose Utilization for Improved Bioproduction in Corynebacterium glutamicum

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Fructose utilization in Corynebacterium glutamicum starts with its uptake and concomitant phosphorylation via the phosphotransferase system (PTS) to yield intracellular fructose 1-phosphate, which enters glycolysis upon ATP-dependent phosphorylation to ...
Irene Krahn   +11 more
doaj   +1 more source

Highly efficient fermentation of 5-keto-d-fructose with Gluconobacter oxydans at different scales

open access: yesMicrobial Cell Factories, 2022
Background The global market for sweeteners is increasing, and the food industry is constantly looking for new low-caloric sweeteners. The natural sweetener 5-keto-d-fructose is one such candidate.
Svenja Battling   +8 more
doaj   +1 more source

Glucose versus fructose metabolism in the liver measured with deuterium metabolic imaging

open access: yesFrontiers in Physiology, 2023
Chronic intake of high amounts of fructose has been linked to the development of metabolic disorders, which has been attributed to the almost complete clearance of fructose by the liver.
Arjan D. Hendriks   +5 more
doaj   +1 more source

Fructose Metabolism in Cancer

open access: yesCells, 2020
The interest in fructose metabolism is based on the observation that an increased dietary fructose consumption leads to an increased risk of obesity and metabolic syndrome. In particular, obesity is a known risk factor to develop many types of cancer and
Nils Krause, Andre Wegner
doaj   +1 more source

Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro

open access: yesNutrition & Diabetes, 2021
Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigated. The goals
Lorna J. Daniels   +12 more
doaj   +1 more source

Oenothein B in Eucalyptus Leaf Extract Suppresses Fructose Absorption in Caco-2 Cells

open access: yesMolecules, 2021
Inhibition of fructose absorption may suppress adiposity and adiposity-related diseases caused by fructose ingestion. Eucalyptus leaf extract (ELE) inhibits intestinal fructose absorption (but not glucose absorption); however, its active compound has not
Keiichiro Sugimoto   +8 more
doaj   +1 more source

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