Results 11 to 20 of about 372,352 (396)
International Journal of Molecular Sciences, 2021 Chronic diseases represent a major challenge in world health. Metabolic syndrome is a constellation of disturbances affecting several organs, and it has been proposed to be a liver-centered condition.
P. Muriel +2 more
semanticscholar +3 more sources
Dietary Fructose and Fructose-Induced Pathologies.
Annual Review of Nutrition, 2022 The consumption of fructose as sugar and high-fructose corn syrup has markedly increased during the past several decades. This trend coincides with the exponential rise of metabolic diseases, including obesity, nonalcoholic fatty liver disease ...
Sunhee Jung +3 more
semanticscholar +5 more sources
Fructose and NAFLD: The Multifaceted Aspects of Fructose Metabolism [PDF]
Nutrients, 2017 Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose is both a substrate and an inducer of hepatic de novo lipogenesis.
P. Jegatheesan, J. de Bandt
semanticscholar +4 more sources
Molecular and Cellular Pediatrics, 2016 Incomplete intestinal absorption of fructose might lead to abdominal complaints such as pain, flatulence and diarrhoea. Whether defect fructose transporters such as GLUT5 or GLUT2 are involved in the pathogenesis of fructose malabsorption is a matter of debate.
Karolin Ebert, Heiko Witt
openaire +5 more sources
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Nature Communications, 2021 Fructose intake has increased substantially throughout the developed world and is associated with obesity, type 2 diabetes and non-alcoholic fatty liver disease. Currently, our understanding of the metabolic and mechanistic implications for immune cells,
N. Jones +15 more
semanticscholar +1 more source
Nutrition & Metabolism, 2013 Whether dietary fructose (as sucrose or high fructose corn syrup) has unique effects separate from its role as carbohydrate, or, in fact, whether it can be considered inherently harmful, even a toxin, has assumed prominence in nutrition. Much of the popular and scientific media have already decided against fructose and calls for regulation and taxation
Eugene J. Fine +2 more
openaire +3 more sources
Fructose stimulated de novo lipogenesis is promoted by inflammation
Nature Metabolism, 2020 Benign hepatosteatosis, affected by lipid uptake, de novo lipogenesis and fatty acid (FA) oxidation, progresses to non-alcoholic steatohepatitis (NASH) on stress and inflammation.
Jelena Todoric +25 more
semanticscholar +1 more source
Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant
Acta Crystallographica Section D: Biological Crystallography, 2008 The X-ray crystallographic structure of a dimer variant of fructose-1,6-bisphosphate aldolase demonstrates a stable oligomer that mirrors half of the native tetramer. The presence of product demonstrates that this is an active form.
Manashi Sherawat +2 more
semanticscholar +1 more source
Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]
, 2019 Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat +12 more
core +1 more source
Global analysis of mannitol 2-dehydrogenase in lactobacillus reuteri crl 1101 during mannitol production through enzymatic, genetic and proteomic approaches [PDF]
, 2017 Several plants, fungi, algae, and certain bacteria produce mannitol, a polyol derived from fructose. Mannitol has multiple industrial applications in the food, pharmaceutical, and medical industries, being mainly used as a non-metabolizable sweetener in ...
Bleckwedel, Juliana +6 more
core +7 more sources