Results 21 to 30 of about 395,783 (395)

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Nature, 2017
The major energy source for most cells is glucose, from which ATP is generated via glycolysis and/or oxidative metabolism. Glucose deprivation activates AMP-activated protein kinase (AMPK), but it is unclear whether this activation occurs solely via ...
Chensong Zhang, S. Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Zhichao Wang, A. Gray, Teng Ma, Jiwen Cui, Jin-Wei Feng, Mingjiang Zhu, Yu-Qing Wu, T. Y. Li, Zhiyun Ye, Shuyong Lin, H. Yin, Hai-long Piao, D. Hardie, Sheng-Cai Lin   +18 more
semanticscholar   +1 more source

The ecologic validity of fructose feeding trials: Supraphysiological feeding of fructose in human trials requires careful consideration when drawing conclusions on cardiometabolic risk

Frontiers in Nutrition, 2015
Background: Select trials of fructose overfeeding have been used to implicate fructose as a driver of cardiometabolic risk.Objective: We examined temporal trends of fructose dose in human controlled feeding trials of fructose and cardiometabolic risk ...
Vivian L Choo, Vivian L Choo, John L Sievenpiper, John L Sievenpiper, John L Sievenpiper   +4 more
doaj   +1 more source

Effects of fructose-containing sweeteners on fructose intestinal, hepatic, and oral bioavailability in dual-catheterized rats.

PLoS ONE, 2018
ObjectiveFructose is commonplace in Western diets and is consumed primarily through added sugars as sucrose or high fructose corn syrup. High consumption of fructose has been linked to the development of metabolic disorders, such as cardiovascular ...
Leah R Villegas, Christopher J Rivard, Brandi Hunter, Zhiying You, Carlos Roncal, Melanie S Joy, MyPhuong T Le   +6 more
doaj   +1 more source

Effect of cyclosporine on hepatic energy status and on fructose metabolism after portacaval shunt in dog as monitored by phosphorus‐31 nuclear magnetic resonance spectroscopy in vivo [PDF]

, 1991
The effect of cyclosporin A on the hepatic energy status and intracellular pH of the liver and its response to a fructose challenge has been investigated using in vivo phosphorus‐31 nuclear magnetic resonance spectroscopy in dogs.
Atkinson, Avison, Baldassarri, Bode, Bäckman, Calne, Cohen, Evelhoch, Francavilla, Grant, Harder, Iles, Iles, Kahn, Kim, Kim, Klintmalm, Laupacis, Loertscher, Lorber, Makowka, Mazzaferro, Otte, Powles, Roos, Rossaro, Schade, Seo, Stacey, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Thompson, Van Thiel, Ziegler   +37 more
core   +1 more source

Effects of fructose added to an oral glucose tolerance test on plasma glucose excursions in healthy adults

Metabolism Open, 2023
Background and objective: Previous experimental studies have shown that fructose interacts with glucose metabolism by increasing hepatic glucose uptake. However, human studies investigating the effects of small (‘catalytic’) amounts of fructose, added to
Amée M. Buziau, Jean L.J.M. Scheijen, Coen D.A. Stehouwer, Casper G. Schalkwijk, Martijn C.G.J. Brouwers   +4 more
doaj   +1 more source

Protective Role of S-Adenosylmethionine Against Fructose-Induced Oxidative Damage in Obesity [PDF]

, 2017
Introduction. It has been shown that S-adenosylmethionine (S-AMe) stimulates glutathione synthesis and increases cell resistance to the cytotoxic action of free radicals and pro-inflammatory cytokines. The aim of this study was to determine the effect of
Bratoeva, Kameliya Zh, Donev, Ivan S, Merdzhanova, Albena V, Radanova, Mariya A   +3 more
core   +4 more sources

The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights

Nutrients, 2021
Non-alcoholic fatty liver disease (NAFLD) represents the result of hepatic fat overload not due to alcohol consumption and potentially evolving to advanced fibrosis, cirrhosis, and hepatocellular carcinoma.
A. Federico, V. Rosato, M. Masarone, P. Torre, M. Dallio, M. Romeo, M. Persico   +6 more
semanticscholar   +1 more source

GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

Cancer & Metabolism, 2021
Background Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate.
Roger J. Liang, Samuel Taylor, Navid Nahiyaan, Junho Song, Charles J. Murphy, Ezequiel Dantas, Shuyuan Cheng, Ting-Wei Hsu, Shakti Ramsamooj, Rahul Grover, Seo-Kyoung Hwang, Bryan Ngo, Lewis C. Cantley, Kyu Y. Rhee, Marcus D. Goncalves   +14 more
doaj   +1 more source

Heterogeneity in Metabolic Responses to Dietary Fructose

Frontiers in Genetics, 2019
Consumption of fructose has dramatically increased in past few decades in children and adults. Increasing evidence indicates that added sugars (particularly fructose) have adverse effects on metabolism and lead to numerous cardiometabolic diseases ...
Ruixue Hou, Chinmayee Panda, V. Saroja Voruganti   +2 more
doaj   +1 more source

Synthesis of fructo-oligosaccharides using grape must and sucrose as raw materials [PDF]

, 2019
Grape must market has been rising and there is an increasing interest to use it as a natural replacement for traditional sugars. Food or beverages with prebiotic compounds, including fructo-oligosaccharides (FOS), emerge as an alternative for the new ...
Gomez Zavaglia, Andrea, Kakisu, Emiliano Javier, Romano, Nelson Gastón, Ureta, María Micaela   +3 more
core   +1 more source