Results 31 to 40 of about 30,141 (201)

Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum

Frontiers in Neurology, 2022
IntroductionFrontotemporal dementia (FTD) is considered to be part of a continuum with amyotrophic lateral sclerosis (ALS). Many genes are associated with both ALS and FTD. Yet, many genes associated with ALS have not been shown to cause FTD. We aimed to
Miguel Tábuas-Pereira, Miguel Tábuas-Pereira, Miguel Tábuas-Pereira, Isabel Santana, Isabel Santana, Isabel Santana, Isabel Santana, Elizabeth Gibbons, Kimberly Paquette, Maria Rosário Almeida, Inês Baldeiras, Inês Baldeiras, Inês Baldeiras, Inês Baldeiras, Jose Bras, Jose Bras, Rita Guerreiro, Rita Guerreiro   +17 more
doaj   +1 more source

FTD spectrum: Neuroimaging across the FTD spectrum [PDF]

, 2019
Frontotemporal dementia is a complex and heterogeneous neurodegenerative disease that encompasses many clinical syndromes, pathological diseases, and genetic mutations. Neuroimaging has played a critical role in our understanding of the underlying pathophysiology of frontotemporal dementia and provided biomarkers to aid diagnosis. Early studies defined
openaire   +2 more sources

Transcriptomic and Network Meta-Analysis of Frontotemporal Dementias

Frontiers in Molecular Neuroscience, 2021
Frontotemporal lobar degeneration (FTLD), also known as frontotemporal dementia (FTD), results in a progressive decline in executive function, leading to behavioral changes, speech problems, and movement disorders.
Virginie Bottero, Fahed Alrafati, Jose A. Santiago, Judith A. Potashkin   +3 more
doaj   +1 more source

Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants

BMC Neuroscience, 2020
Background Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory, and behavior.
Lalitha Venkataraman, Ping He, Galam Khan, Brent T. Harris, Michael R. Sierks   +4 more
doaj   +1 more source

Genetic prion diseases presenting as frontotemporal dementia: clinical features and diagnostic challenge

Alzheimer’s Research & Therapy, 2022
Background To elucidate the clinical and ancillary features of genetic prion diseases (gPrDs) presenting with frontotemporal dementia (FTD) to aid early identification.
Zhongyun Chen, Min Chu, Li Liu, Jing Zhang, Yu Kong, Kexin Xie, Yue Cui, Hong Ye, Junjie Li, Lin Wang, Liyong Wu   +10 more
doaj   +1 more source

A case of familial frontotemporal dementia caused by a progranulin gene mutation

Clinical Parkinsonism & Related Disorders, 2023
After Alzheimer’s disease, Frontotemporal dementia (FTD) is the most common cause of early-onset dementia. Several genetic mutations have been identified in familial FTD, with mutations in progranulin (GRN) accounting for approximately 20–25% of familial
Lauryn Currens, Nigel Harrison, Maria Schmidt, Halima Amjad, Weiyi Mu, Sonja W. Scholz, Jee Bang, Alexander Pantelyat   +7 more
doaj   +1 more source

Red herrings in the diagnosis of frontotemporal dementia: A case of probable bipolar disorder evolving into frontotemporal dementia

Journal of Geriatric Mental Health, 2018
Bipolar illness and Frontotemporal dementia (FTD) share many common features. The clinical features of mania such as excessive cheerfulness, hyper-sexuality and overspending can mimic impaired judgement and loss of inhibition seen in FTD.
Shiva Shanker Reddy Mukku, Manjula Simiyon, Umamaheswari Vanamoorthy, Santosh Loganathan, Mathew Varghese   +4 more
doaj   +1 more source

ETF FTD library --v3--

, 2021
ETF FTD library --v3-
Goku
core   +1 more source

FTD Grammar Graph

International Journal of Computer Mathematics, 2003
The notations of (1) KBO: Knowledge Based Object, (2) FTD: Formally Technology Dependent, (3) WW KBO: Window Womb KBO, (4) PL KBO: Programming Language KBO, (5) APM KBO: Abstract Processing Machine KBO, and (6) AIPM KBO: Abstract Information Processing Mechanism KBO, were studied in U¨nlu¨ [1-3]. Let the meaning of an arbitrarily chosen X :=\langle X^o,
openaire   +3 more sources

Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD

, 2022
Protein aggregation is a hallmark of neurodegenerative diseases (NDs), including Amyotrophic Lateral Sclerosis/Frontotemporal dementia (ALS/FTD). The C9ORF72-hexanucleotide expansion G4C2 represents one of the most frequent genetic causes of ALS/FTD ...
M. Cozzi, M. Galbiati, V. Crippa, M. Piccolella, A. Poletti, M. Chierichetti, B. Tedesco, P. Pramaggiore, P. Rusmini, V. Ferrari, R. Cristofani, F. Mina, E. Casarotto   +12 more
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