Results 1 to 10 of about 1,628 (214)

Antiproliferative Activity of Fucan Nanogel [PDF]

Marine Drugs, 2012
Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses.
Francisco Miguel Gama, Hugo Alexandre Oliveira Rocha, Paula Pereira, Silvia Santos Pedrosa, Arthur Anthunes Jacome Vidal, Ruth Medeiros Oliveira, Dayanne Lopes Gomes, Jailma Almeida-Lima, Nednaldo Dantas-Santos   +8 more
doaj   +8 more sources

Anti-Inflammatory Activity of Fucan from Spatoglossum schröederi in a Murine Model of Generalized Inflammation Induced by Zymosan [PDF]

Marine Drugs, 2023
Fucans from marine algae have been the object of many studies that demonstrated a broad spectrum of biological activities, including anti-inflammatory effects. The aim of this study was to verify the protective effects of a fucan extracted from the brown
Ana Katarina Andrade Silva, Cássio Ricardo de Medeiros Souza, Hylarina Montenegro Diniz Silva, Jéssica Teixeira Jales, Lucas Alves de Souza Gomez, Ericka Janine Dantas da Silveira, Hugo Alexandre Oliveira Rocha, Janeusa Trindade Souto   +7 more
doaj   +2 more sources

Silver Nanoparticles Containing Fucoidan Synthesized by Green Method Have Anti-Trypanosoma cruzi Activity [PDF]

Nanomaterials, 2022
The brown seaweed Spatoglossum schröederi synthesizes three bioactive fucoidans, the most abundant of which is fucan A. This fucoidan was extracted and its identity was confirmed by chemical analysis, Fourier-transform infrared spectroscopy (FTIR), and ...
Adriana Oliveira Souza, Johny Wysllas de Freitas Oliveira, Claudia Jéssica Gonsalves Moreno, Mayra Jane Campos de Medeiros, Marília Medeiros Fernandes-Negreiros, Flavia Roberta Monteiro Souza, Daniel Lima Pontes, Marcelo Sousa Silva, Hugo Alexandre Oliveira Rocha   +8 more
doaj   +2 more sources

Monoclonal antibodies directed to fucoidan preparations from brown algae. [PDF]

PLoS ONE, 2015
Cell walls of the brown algae contain a diverse range of polysaccharides with useful bioactivities. The precise structures of the sulfated fucan/fucoidan group of polysaccharides and their roles in generating cell wall architectures and cell properties ...
Thomas A Torode, Susan E Marcus, Murielle Jam, Thierry Tonon, Richard S Blackburn, Cécile Hervé, J Paul Knox   +6 more
doaj   +13 more sources

Evaluation of Anti-Nociceptive and Anti-Inflammatory Activities of a Heterofucan from Dictyota menstrualis [PDF]

Marine Drugs, 2013
Fucan is a term that defines a family of homo- and hetero-polysaccharides containing sulfated l-fucose in its structure. In this work, a heterofucan (F2.0v) from the seaweed, Dictyota menstrualis, was evaluated as an antinociceptive and anti-inflammatory
Helena Bonciani Nader, Hugo Alexandre Oliveira Rocha, Edda Lisboa Leite, Luciana Guimarães Alves Filgueira, Juliana Luporini Dreyfuss, Dayanne Lopes Gomes, Sara Lima Cordeiro, Ivan Rui Lopes Albuquerque   +7 more
doaj   +4 more sources

A fucan from the brown seaweed Spatoglossum schröederi inhibits Chinese hamster ovary cell adhesion to several extracellular matrix proteins [PDF]

Brazilian Journal of Medical and Biological Research, 2001
Fucans, a family of sulfated polysaccharides present in brown seaweed, have several biological activities. Their use as drugs would offer the advantage of no potential risk of contamination with viruses or particles such as prions.
H.A.O. Rocha, C.R.C. Franco, E.S. Trindade, L.C.M. Carvalho, S.S. Veiga, E.L. Leite, C.P. Dietrich, H.B. Nader   +7 more
doaj   +3 more sources

Effects of Cooking Methods on the Flavor Characteristics of Volatiles of <i>Boletus edulis</i> Based on GC-IMS, E-Nose, and Sensory Evaluation. [PDF]

Food Sci Nutr
This study successfully established characteristic fingerprints of volatile flavor components in Boletus edulis subjected to different cooking methods. Using principal component analysis (PCA) to quantitatively evaluate changes in flavor substances, and combined with a sensory evaluation system, it comprehensively assessed the impact of cooking ...
Wu X, Wang J, Liu H, Sun F, Liu F, He J, Tian F, Gan C.   +7 more
europepmc   +2 more sources

Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide [PDF]

Nature Communications
Sulfated fucan is one of the most recalcitrant polysaccharides. The molecular mechanism underlying the endo-1,3-fucanase, which plays a critical role in the breakdown of sulfated fucan, remains unexplained.
Guangning Chen, Jingjing Shen, Xinyu Li, Menghui Sun, Sheng Dong, Ying Sun, Achiraya Khamleng, Xuanwei Mei, Yuying Zhang, Guanchen Liu, Fangyi Chen, Xiao Song, Kaimeng Liu, Yingang Feng, Changhu Xue, Yaoguang Chang   +15 more
doaj   +2 more sources

Partial characterization and anticoagulant activity of a heterofucan from the brown seaweed Padina gymnospora [PDF]

Brazilian Journal of Medical and Biological Research, 2005
The brown algae Padina gymnospora contain different fucans. Powdered algae were submitted to proteolysis with the proteolytic enzyme maxataze. The first extract of the algae was constituted of polysaccharides contaminated with lipids, phenols, etc ...
T.M.A. Silva, L.G. Alves, K.C.S. de Queiroz, M.G.L. Santos, C.T. Marques, S.F. Chavante, H.A.O. Rocha, E.L. Leite   +7 more
doaj   +5 more sources

Analysis Methods and Structure–Activity Relationships of Polysaccharides in Sea Cucumber: A Review [PDF]

Marine Drugs
Sea cucumber polysaccharide is a kind of heteropolysaccharide rich in sulfate groups, which has complex structures and various biological activities. Its biological activity is closely related to its chemical composition, molecular weight, and sulfated ...
Xingyu Gu, Pengneng Yu, Yuyang Li, Rui Feng, Dong Lv, Zhuoran Song, Tong Geng, Yubo Qin, Ying Li, Zhibo Li, Qiancheng Zhao   +10 more
doaj   +2 more sources