Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber [PDF]
Marine Drugs, 2015 Sulfated fucans, the complex polysaccharides, exhibit various biological activities. Herein, we purified two fucans from the sea cucumbers Holothuria edulis and Ludwigothurea grisea. Their structures were verified by means of HPGPC, FT-IR, GC–MS and NMR.
Mingyi Wu, Longyan Zhao, Jinhua Zhao
exaly +4 more sources
Monoclonal antibodies directed to fucoidan preparations from brown algae. [PDF]
PLoS ONE, 2015 Cell walls of the brown algae contain a diverse range of polysaccharides with useful bioactivities. The precise structures of the sulfated fucan/fucoidan group of polysaccharides and their roles in generating cell wall architectures and cell properties ...
Thomas A Torode +6 more
doaj +13 more sources
Antiproliferative Activity of Fucan Nanogel [PDF]
Marine Drugs, 2012 Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses.
Francisco Miguel Gama +8 more
doaj +4 more sources
A fucan from the brown seaweed Spatoglossum schröederi inhibits Chinese hamster ovary cell adhesion to several extracellular matrix proteins [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Fucans, a family of sulfated polysaccharides present in brown seaweed, have several biological activities. Their use as drugs would offer the advantage of no potential risk of contamination with viruses or particles such as prions.
H.A.O. Rocha +7 more
doaj +3 more sources
Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide [PDF]
Nature CommunicationsSulfated fucan is one of the most recalcitrant polysaccharides. The molecular mechanism underlying the endo-1,3-fucanase, which plays a critical role in the breakdown of sulfated fucan, remains unexplained.
Guangning Chen +15 more
doaj +2 more sources
Partial characterization and anticoagulant activity of a heterofucan from the brown seaweed Padina gymnospora [PDF]
Brazilian Journal of Medical and Biological Research, 2005 The brown algae Padina gymnospora contain different fucans. Powdered algae were submitted to proteolysis with the proteolytic enzyme maxataze. The first extract of the algae was constituted of polysaccharides contaminated with lipids, phenols, etc ...
T.M.A. Silva +7 more
doaj +5 more sources
Analysis Methods and Structure–Activity Relationships of Polysaccharides in Sea Cucumber: A Review [PDF]
Marine DrugsSea cucumber polysaccharide is a kind of heteropolysaccharide rich in sulfate groups, which has complex structures and various biological activities. Its biological activity is closely related to its chemical composition, molecular weight, and sulfated ...
Xingyu Gu +10 more
doaj +2 more sources
Evaluation of Anti-Nociceptive and Anti-Inflammatory Activities of a Heterofucan from Dictyota menstrualis [PDF]
Marine Drugs, 2013 Fucan is a term that defines a family of homo- and hetero-polysaccharides containing sulfated l-fucose in its structure. In this work, a heterofucan (F2.0v) from the seaweed, Dictyota menstrualis, was evaluated as an antinociceptive and anti-inflammatory
Helena Bonciani Nader +7 more
doaj +4 more sources
Fucose-Rich Sulfated Polysaccharides from Two Vietnamese Sea Cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera: Structures and Anticoagulant Activity [PDF]
Marine Drugs, 2022 Fucosylated chondroitin sulfates (FCSs) FCS-BA and FCS-HS, as well as fucan sulfates (FSs) FS-BA-AT and FS-HS-AT were isolated from the sea cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera, respectively.
Nadezhda E. Ustyuzhanina +11 more
doaj +2 more sources
Automated Synthesis of Algal Fucoidan Oligosaccharides. [PDF]
J Am Chem SocFucoidan, a sulfated polysaccharide found in algae, plays a central role in marine carbon sequestration and exhibits a wide array of bioactivities. However, the molecular diversity and structural complexity of fucoidan hinder precise structure-function ...
Crawford CJ +5 more
europepmc +7 more sources