Results 11 to 20 of about 17,627 (184)
Sulfated fucan as support for antibiotic immobilization [PDF]
Brazilian Journal of Medical and Biological Research, 2004 Xylofucoglucuronan from Spatoglossum schröederi algae was tested as a support for antibiotic immobilization. The polysaccharide (20 mg in 6 ml) was first activated using carbodiimide, 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide methiodide (20 mg in 2 ...
P.M. Araújo +5 more
doaj +6 more sources
Antiproliferative Activity of Fucan Nanogel [PDF]
Marine Drugs, 2012 Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses.
Francisco Miguel Gama +8 more
doaj +2 more sources
Marine Drugs, 2018 The anticoagulant and antithrombotic properties of three structurally correlated sea urchin-derived 3-linked sulfated α-glycans and their low molecular-weight derivatives were screened comparatively through various in vitro and in vivo methods ...
Ariana A. Vasconcelos +6 more
doaj +2 more sources
Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight [PDF]
Marine Drugs, 2019 Background: Sulfated fucans show interesting effects in the treatment of ocular diseases (e.g., age-related macular degeneration), depending on their chemical structure.
Philipp Dörschmann +3 more
doaj +2 more sources
Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis [PDF]
Glycobiology, 2018 Metastasis is responsible for the majority of cancer-associated deaths, though only a very small number of tumor cells are able to efficiently complete all the steps of that process. Tumor cell survival in the bloodstream is one of the limiting aspects of the metastatic cascade.
Felipe C O B Teixeira +5 more
core +6 more sources
Heterofucan from Sargassum filipendula Induces Apoptosis in HeLa Cells
Marine Drugs, 2011 Fucan is a term used to denominate a family of sulfated polysaccharides rich in sulfated L-fucose. Heterofucan SF-1.5v was extracted from the brown seaweed Sargassum filipendula by proteolytic digestion followed by sequential acetone precipitation.
Hugo Alexandre Oliveira Rocha +11 more
doaj +2 more sources
Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum [PDF]
Phytochemistry, 2006 A sulfated fucan containing fraction (SmWE) was isolated from water extract of the brown seaweed Stoechospermum marginatum collected from the Arabian Sea. Anion exchange chromatography of the crude fraction results in the production of a sulfated fucan (F3) having a molecular mass of 40 kDa and specific rotation [alpha]D(30) - 124 degrees (c 0.5, H2O).
Adhikari, Utpal +5 more
openaire +4 more sources
Heterofucans from Dictyota menstrualis have anticoagulant activity [PDF]
Brazilian Journal of Medical and Biological Research, 2004 Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins.
I.R.L. Albuquerque +5 more
doaj +2 more sources
A fucan from the brown seaweed Spatoglossum schröederi inhibits Chinese hamster ovary cell adhesion to several extracellular matrix proteins [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Fucans, a family of sulfated polysaccharides present in brown seaweed, have several biological activities. Their use as drugs would offer the advantage of no potential risk of contamination with viruses or particles such as prions.
H.A.O. Rocha +7 more
doaj +3 more sources
Marine Drugs, 2018 Immunosuppression derived after cytostatics application in cancer chemotherapy is considered as an adverse side effect that leads to deterioration of quality of life and risk of infectious diseases.
Natalia Yu. Anisimova +7 more
doaj +2 more sources