Results 11 to 20 of about 959 (203)

Monoclonal antibodies directed to fucoidan preparations from brown algae. [PDF]

PLoS ONE, 2015
Cell walls of the brown algae contain a diverse range of polysaccharides with useful bioactivities. The precise structures of the sulfated fucan/fucoidan group of polysaccharides and their roles in generating cell wall architectures and cell properties ...
Thomas A Torode, Susan E Marcus, Murielle Jam, Thierry Tonon, Richard S Blackburn, Cécile Hervé, J Paul Knox   +6 more
doaj   +4 more sources

A fucan from the brown seaweed Spatoglossum schröederi inhibits Chinese hamster ovary cell adhesion to several extracellular matrix proteins [PDF]

Brazilian Journal of Medical and Biological Research, 2001
Fucans, a family of sulfated polysaccharides present in brown seaweed, have several biological activities. Their use as drugs would offer the advantage of no potential risk of contamination with viruses or particles such as prions.
H.A.O. Rocha, C.R.C. Franco, E.S. Trindade, L.C.M. Carvalho, S.S. Veiga, E.L. Leite, C.P. Dietrich, H.B. Nader   +7 more
doaj   +3 more sources

Fucan effect on CHO cell proliferation and migration

Carbohydrate Polymers, 2013
Fucan is a term used to denominate sulfated L-fucose rich polysaccharides. Here, a heterofucan, named fucan B, was extracted from the Spatoglossum schröederi seaweed. This 21.5 kDa galactofucan inhibited CHO-K1 proliferation and migration when fibronectin was the substrate.
Nobre, Leonardo Thiago Duarte Barreto, Vidal, Arthur Anthunes Jacome, Almeida-Lima, Jailma, Oliveira, Ruth Medeiros, Paredes-Gamero, Edgar Jean, Medeiros, Valquiria Pereira, Trindade, Edvaldo Silva, Franco, Celia Regina Cavichiolo, Nader, Helena Bonciani, Rocha, Hugo Alexandre Oliveira   +9 more
openaire   +3 more sources

Heterofucan from Sargassum filipendula Induces Apoptosis in HeLa Cells

Marine Drugs, 2011
Fucan is a term used to denominate a family of sulfated polysaccharides rich in sulfated L-fucose. Heterofucan SF-1.5v was extracted from the brown seaweed Sargassum filipendula by proteolytic digestion followed by sequential acetone precipitation.
Hugo Alexandre Oliveira Rocha, Edda Lisboa Leite, Ivan Rui Lopes Albuquerque, Raniere Fagundes Melo-Silveira, Jailma Almeida-Lima, Rafael Barros Gomes Camara, Leonardo Thiago Duarte Barreto Nobre, Mariana Santana Santos Pereira Costa, Nednaldo Dantas-Santos, Leandro Silva Costa, Cinthia Beatrice Silva Telles, Ruth Medeiros Oliveira   +11 more
doaj   +2 more sources

Heterofucans from Dictyota menstrualis have anticoagulant activity [PDF]

Brazilian Journal of Medical and Biological Research, 2004
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins.
I.R.L. Albuquerque, K.C.S. Queiroz, L.G. Alves, E.A. Santos, E.L. Leite, H.A.O. Rocha   +5 more
doaj   +2 more sources

Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber

Marine Drugs, 2015
Sulfated fucans, the complex polysaccharides, exhibit various biological activities. Herein, we purified two fucans from the sea cucumbers Holothuria edulis and Ludwigothurea grisea. Their structures were verified by means of HPGPC, FT-IR, GC–MS and NMR.
Mingyi Wu, Li Xu, Longyan Zhao, Chuang Xiao, Na Gao, Lan Luo, Lian Yang, Zi Li, Lingyun Chen, Jinhua Zhao   +9 more
doaj   +2 more sources

Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight [PDF]

Marine Drugs, 2019
Background: Sulfated fucans show interesting effects in the treatment of ocular diseases (e.g., age-related macular degeneration), depending on their chemical structure.
Philipp Dörschmann, Georg Kopplin, Johann Roider, Alexa Klettner   +3 more
doaj   +2 more sources

Antioxidant and Antiproliferative Activities of Heterofucans from the Seaweed Sargassum filipendula

Marine Drugs, 2011
Fucan is a term used to denominate a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups. We obtained five heterofucans from Sargassum filipendula by proteolytic digestion followed by sequential acetone ...
Hugo Alexandre Oliveira Rocha, Giulianna Paiva Viana Andrade, Ivan Rui Lopes Albuquerque, Ruth Medeiros Oliveira, Raniere Fagundes Melo-Silveira, Jailma Almeida-Lima, Sara Lima Cordeiro, Mariana Santana Santos Pereira Costa, Rafael Barros Gomes Camara, Nednaldo Dantas-Santos, Gabriel Pereira Fidelis, Cinthia Beatrice Silva Telles, Leandro Silva Costa   +12 more
doaj   +2 more sources

Anticoagulant and Antithrombotic Properties of Three Structurally Correlated Sea Urchin Sulfated Glycans and Their Low-Molecular-Weight Derivatives

Marine Drugs, 2018
The anticoagulant and antithrombotic properties of three structurally correlated sea urchin-derived 3-linked sulfated α-glycans and their low molecular-weight derivatives were screened comparatively through various in vitro and in vivo methods ...
Ariana A. Vasconcelos, Isabela D. Sucupira, Alessandra L. Guedes, Ismael N. Queiroz, Flavia S. Frattani, Roberto J. Fonseca, Vitor H. Pomin   +6 more
doaj   +2 more sources

The Effect of Sulfated (1→3)-α-l-Fucan from the Brown Alga Saccharina cichorioides Miyabe on Resveratrol-Induced Apoptosis in Colon Carcinoma Cells

Marine Drugs, 2013
Accumulating data clearly indicate that the induction of apoptosis by nontoxic natural compounds is a potent defense against the development and progression of many malignancies, including colon cancer.
Olesia S. Vishchuk, Svetlana P. Ermakova, Tatyana N. Zvyagintseva   +2 more
doaj   +2 more sources