Inflammatory bowel disease is associated with intestinal dysbiosis and with elevated antibody production toward microbial epitopes. The underlying processes linking the gut microbiota with inflammation are still unclear.
Katharina Kappler+4 more
doaj +1 more source
Regulatory activity revealed by dynamic correlations in gene expression noise [PDF]
Gene regulatory interactions are context dependent, active in some cellular states but not in others. Stochastic fluctuations, or 'noise', in gene expression propagate through active, but not inactive, regulatory links^(1,2).
Cox, Robert Sidney, III+4 more
core +2 more sources
Application of Seaweed Organic Components Increases Tolerance to Fe Deficiency in Tomato Plants
The beneficial effects of seaweed extracts have been related to plant growth regulators present in seaweeds. However, algae extracts comprise other organic compounds such as phenols, mannitol, alginates, laminarins, and fucoidans that may have a relevant
Sandra Carrasco-Gil+3 more
doaj +1 more source
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Altschuler Y.+8 more
core +2 more sources
Objective:Sialic acid, hexoses, hexosamines and fucose are components of glycoprotein, glycolipid and/or ganglioside. These glycoconjugates are essential components of cellular membrane and receptors, which are required for normal cellular activities ...
Umar Faruk Magaji+3 more
doaj +1 more source
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter+2 more
core +1 more source
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan+9 more
core +2 more sources
A set of conjugation‐ready Staphylococcus aureus serotype 5 oligosaccharides has been generated using a stereoselective [3 + 3n] glycosylation strategy. The structures differ in chain length (up to three repeating units) and O‐ and N‐acetylation pattern.
Kitt E. Østerlid+15 more
wiley +2 more sources
Glycosylated proteins preserved over millennia: N-glycan analysis of Tyrolean Iceman, Scythian Princess and Warrior. [PDF]
An improved understanding of glycosylation will provide new insights into many biological processes. In the analysis of oligosaccharides from biological samples, a strict regime is typically followed to ensure sample integrity.
An, Hyun Joo+11 more
core +1 more source
Structure of the fucose mutarotase fromStreptococcus pneumoniaein complex with
Streptococcus pneumoniaerelies on a variety of carbohydrate-utilization pathways for both colonization of its human host and full virulence during the development of invasive disease. One such pathway is the fucose-utilization pathway, a component of which is fucose mutarotase (SpFcsU), an enzyme that performs the interconversion between α-L-fucose and
Alisdair B. Boraston, Melanie A. Higgins
openaire +3 more sources