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Structure and Anticoagulant Activity of a Fucosylated Chondroitin Sulfate from Echinoderm [PDF]
Paulo A.S. Mourão +6 more
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Anti-Cancer Activity of Marine-Derived Fucosylated Chondroitin Sulfates in Ovarian Cancer Cell Spheroid Formation and Notch Signaling Inhibition [PDF]
Ovarian cancer is the deadliest gynecological malignancy, with high recurrence rates driven by chemotherapy-resistant cancer stem cells (CSCs). Current therapeutics targeting Notch signaling to inhibit CSC formation have yet to demonstrate clinical ...
Beiner, Daniella
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Host glycoconjugates in Salmonella infection: a bittersweet symphony [PDF]
Galeev, Alibek
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Photochemical depolymerisation of dermatan sulfate and analysis of the generated oligosaccharides [PDF]
August, David P. +3 more
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Chemical Synthesis of Fucosylated Chondroitin Sulfate Oligosaccharides
The Journal of Organic Chemistry, 2020Fucosylated chondroitin sulfates (FuCSs) are a unique type of polysaccharides occurring in sea cucumber that show a variety of biological activities. In particular, well-defined FuCS oligosaccharides, consisting of a trisaccharide repeating unit of β-d-GalNAc(4,6-diS)-(1→4)-[α-l-Fuc(2,4-diS)-(1→3)]-β-d-GlcUA, display potent anticoagulant activity via ...
Liangzhong Zhang +3 more
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Chemical Fucosylation of a Polysaccharide: A Semisynthetic Access to Fucosylated Chondroitin Sulfate
Biomacromolecules, 2015Chemical O-glycosylation of polysaccharides is an almost unexplored reaction. This is mainly due to the difficulties in derivatizing such complex biomacromolecules in a quantitative manner and with a fine control of the obtained structural parameters.
LAEZZA, ANTONIO +6 more
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