Results 11 to 20 of about 911 (170)

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection [PDF]

open access: yes, 2021
Certain sulfated glycans, including those from marine sources, can show potential effects against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea cucumber Pentacta pygmaea (PpFucCS) (MW ∼10.60 kDa) was isolated and ...
Dwivedi, Rohini   +3 more
core   +2 more sources

Glycans and glycosaminoglycans in neurobiology: key regulators of neuronal cell function and fate [PDF]

open access: yes, 2018
The aim of the present study was to examine the roles of l-fucose and the glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate (CS/DS) with selected functional molecules in neural tissues.
Hayes, Anthony J., Melrose, James
core   +2 more sources

Structure and Anti-Inflammatory Activity of a New Unusual Fucosylated Chondroitin Sulfate from Cucumaria djakonovi

open access: yesMarine Drugs, 2018
Fucosylated chondroitin sulfate CD was isolated from the sea cucumber Cucumaria djakonovi collected from the Avachinsky Gulf of the eastern coast of Kamchatka.
Nadezhda E. Ustyuzhanina   +9 more
doaj   +1 more source

Inhibition of Cytomegalovirus by Pentacta pygmaea Fucosylated Chondroitin Sulfate Depends on Its Molecular Weight

open access: yesViruses, 2023
Many viruses attach to host cells by first interacting with cell surface proteoglycans containing heparan sulfate (HS) glycosaminoglycan chains and then by engaging with specific receptor, resulting in virus entry.
Poonam Sharma   +5 more
doaj   +1 more source

In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa

open access: yesMolecules, 2016
The low-molecular-weight fucosylated chondroitin sulfate (LFCS) was prepared from native fucosylated chondroitin sulfate (FCS), which was extracted and isolated from sea cucumber Cucumaria frondosa, and the anti-cancer mechanism of LFCS on mouse Lewis ...
Xiaoxiao Liu   +9 more
doaj   +1 more source

Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]

open access: yes, 2016
The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier   +3 more
core   +1 more source

Comparison of protein quantification methods for protein encapsulation with ZIF‐8 metal‐organic frameworks

open access: yesBiotechnology Journal, Volume 18, Issue 11, November 2023., 2023
Graphical Abstract and Lay Summary Encapsulation of biomolecules with metal organic frameworks has great potential for therapeutic applications. Biomolecule quantification is necessary for efficacy assessment and optimization. There are many techniques for biomolecule quantification.
Joel Yong   +5 more
wiley   +1 more source

Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate [PDF]

open access: yesCarbohydrate Polymers, 2016
Fucosylated chondroitin sulfates (fCSs) are glycosaminoglycans extracted from sea cucumbers, consisting of chondroitin sulfate E (CSE) backbones and sulfated fucose branches. The biological properties of fCSs could be affected by the sulfation pattern of their fucose branches. In the present study, two fCSs were isolated from sea cucumbers Isostichopus
Wu, Nian   +5 more
openaire   +2 more sources

Antiproliferative activity of glycosaminoglycan-like polysaccharides derived from marine molluscs [PDF]

open access: yes, 2018
Despite the increasing availability of new classes of cancer treatment, such as immuneand targeted therapies, there remains a need for the development of new antiproliferative/cytotoxic drugs with improved pharmacological profiles that can also ...
Gallagher   +3 more
core   +2 more sources

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

open access: yesMass Spectrometry Reviews, Volume 42, Issue 5, Page 1984-2206, September/October 2023., 2023
Abstract This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020.
David J. Harvey
wiley   +1 more source

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