Results 21 to 30 of about 15,330 (252)
Novel Insights Into N-Glycan Fucosylation and Core Xylosylation in C. reinhardtii
Frontiers in Plant Science, 2020 Chlamydomonas reinhardtii (C. reinhardtii) N-glycans carry plant typical β1,2-core xylose, α1,3-fucose residues, as well as plant atypical terminal β1,4-xylose and methylated mannoses. In a recent study, XylT1A was shown to act as core xylosyltransferase,
Anne Oltmanns +7 more
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Acta Biochimica et Biophysica Sinica, 2023 Individuals with spinal cord injury (SCI) suffer from permanent disabilities such as severe motor, sensory and autonomic dysfunction.
Chen Jiewen +7 more
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Establishment and identification of a human megakaryocytic cell line with low Ley expression
Zhongguo shuxue zazhi, 2022 Objective To establish a stable human megakaryocytic cell line with low expression of Ley antigen to further study the role of Ley on activation of platelets.
Huijun ZHU +4 more
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Fucosyltransferases: structure/function studies [PDF]
Glycobiology, 2001 Alpha3-fucosyltransferases (alpha3-FucTs) catalyze the final step in the synthesis of a range of important glycoconjugates that function in cell adhesion and lymphocyte recirculation. Six members of this family of enzymes have been cloned from the human genome, and their expression pattern has been shown to be highly regulated. Each enzyme has a unique
T, de Vries +3 more
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Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment [PDF]
Cytotherapy, 2014 Background aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow or mobilized peripheral blood. However, poor engraftment remains a major obstacle.
Simon N, Robinson +20 more
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Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Abundant surface glycoconjugates play key roles in the infectious cycle of protozoan parasites including Leishmania. Through defining biosynthetic pathways, we identified a fucosyltransferase FUT1 localized to the parasite mitochondrion, an ...
Hongjie Guo +7 more
semanticscholar +1 more source
Genomics of Otitis Media (OM): Molecular Genetics Approaches to Characterize Disease Pathophysiology
Frontiers in Genetics, 2020 Otitis media (OM) is an infective and inflammatory disorder known to be a major cause of hearing impairment across all age groups. Both acute and chronic OM result in substantial healthcare utilization related to antibiotic prescription and surgical ...
Arnaud P. J. Giese +5 more
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Allele frequency of A385T in Fucosyltransferase 2 gene (FUT2) among Southern Thai population [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2020 Fucosyltransferase 2 gene (FUT2) gene plays an important role in control of enzymes that secrete blood type antigen substances. The mutation of FUT2 at nucleotide position 385 from A to T (A385T) combined with secretor phenotype is associated with ...
Darinnat Buathong +2 more
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Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY
Nature Communications, 2023 Kumar and colleagues report cryo-EM structures of Arabidopsis O-fucosyltransferase SPINDLY in its apo and GDP-fucose bound states, revealing distinct active-site features enabling GDP-fucose recognition and surprisingly dynamic conformations that ...
Shivesh Kumar +14 more
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