Frontiers in Nutrition, 2020 Rationale: Human milk oligosaccharides (HMOs) vary among mothers and genetic factors contribute to this variability. We assessed changes in HMO concentrations during the first year of lactation and the relationship with FUT2 Secretor group and FUT3 Lewis
Gregory Lefebvre +9 more
semanticscholar +1 more source
The possibility of positive selection for both F18(+) Escherichia coli and stress resistant pigs opens new perspectives for pig breeding [PDF]
, 2007 International ...
Coddens, Annelies +7 more
core +2 more sources
Structural basis of substrate recognition and catalysis by fucosyltransferase 8
Journal of Biological Chemistry, 2020 Fucosylation of the innermost GlcNAc of N-glycans by fucosyltransferase 8 (FUT8) is an important step in the maturation of complex and hybrid N-glycans.
M. Järvå +7 more
semanticscholar +1 more source
Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]
, 2015 O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi +8 more
core +1 more source
Development, 2020 Root hairs are able to sense soil composition and play an important role in water and nutrient uptake. In Arabidopsis thaliana, root hairs are distributed in the epidermis in a specific pattern, regularly alternating with non-root hair cells in ...
K. V. Mutanwad +2 more
semanticscholar +1 more source
Stage‐specific expression of α1,2‐fucosyltransferase and α1,3‐fucosyltransferase (FT) during mouse embryogenesis [PDF]
European Journal of Biochemistry, 1999 Lex[Galβ1–4(Fucα1–3)GlcNAc] and Ley[Fucα1–2Galβ1–4(Fucα1–3)GlcNAc] are both stage‐specific embryonic antigens. Lex is first detected on the blastomeres of the 8‐cell stage embryo, which correlates with the onset of blastomere compaction. Ley is highly expressed on the surface of the blastocyst, which has been shown to be involved in blastocyst ...
Changhui Ge +7 more
openaire +3 more sources
Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]
, 2013 The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani +58 more
core +9 more sources
Recent Progress on Fucosyltransferase Inhibitors
Mini-Reviews in Medicinal Chemistry, 2012 Fucosyltransferases (FucTs) are enzymes that transfer L-fucose from GDP-fucose to a glycoside or a peptide. They have important roles in a variety of diseases including cancer and autoimmune disorders, viral and bacterial infections and inflammatory processes, and thus they represent important drug targets for the development of agents for the ...
Merino, Pedro +5 more
openaire +4 more sources
Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding [PDF]
, 2007 Fertilization depends on successful binding of the spermatozoa to the zona pellucida of the oocyte. Glycodelin-A inhibits spermatozoa-zona pellucida binding.
Chiu, PCN +8 more
core +1 more source
Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
, 2018 FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R. +9 more
core +1 more source