Results 31 to 40 of about 15,330 (252)

Time of Lactation and Maternal Fucosyltransferase Genetic Polymorphisms Determine the Variability in Human Milk Oligosaccharides

Frontiers in Nutrition, 2020
Rationale: Human milk oligosaccharides (HMOs) vary among mothers and genetic factors contribute to this variability. We assessed changes in HMO concentrations during the first year of lactation and the relationship with FUT2 Secretor group and FUT3 Lewis
Gregory Lefebvre, M. Shevlyakova, A. Charpagne, Julien Marquis, M. Vogel, T. Kirsten, W. Kiess, S. Austin, N. Sprenger, A. Binia   +9 more
semanticscholar   +1 more source

The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer [PDF]

Middle East Journal of Cancer
Colorectal cancer (CRC) ranks as the third most prevalent cancer worldwide and is a leading cause of cancer-related mortality. Since many colon cancers present no significant clinical symptoms, identifying new biomarkers or a set of biological indicators
Durdi Qujeq, Roya Abbasi Natajomrani, Reza Hajihosseini, Vahid Hosseini, Arash Kazemi Veisari, Khadijeh Hoznian   +5 more
doaj   +1 more source

Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases

Journal of Biological Chemistry, 2020
Mammalian Asn-linked glycans are extensively processed as they transit the secretory pathway to generate diverse glycans on cell surface and secreted glycoproteins.
B. M. Boruah, R. Kadirvelraj, Lin Liu, A. Ramiah, Chao Li, Guanghui Zong, Gerlof P. Bosman, Jeong-Yeh Yang, Lai-Xi Wang, G. Boons, Z. A. Wood, K. Moremen   +11 more
semanticscholar   +1 more source

Survey and characterization of nonfunctional alleles of FUT2 in a database

Scientific Reports, 2021
The expression of ABO antigens in human saliva is regulated by the FUT2 gene, which encodes a secretor type α(1,2)fucosyltransferase. Secretors express ABO substrates in saliva and non-secretors do not. Secretor status is an object of concern, especially
Mikiko Soejima, Yoshiro Koda
doaj   +1 more source

Structural basis of substrate recognition and catalysis by fucosyltransferase 8

Journal of Biological Chemistry, 2020
Fucosylation of the innermost GlcNAc of N-glycans by fucosyltransferase 8 (FUT8) is an important step in the maturation of complex and hybrid N-glycans.
M. Järvå, M. Dramicanin, J. Lingford, R. Mao, A. John, K. Jarman, R. Grinter, E. Goddard-Borger   +7 more
semanticscholar   +1 more source

FUT1 variants responsible for Bombay or para-Bombay phenotypes in a database

Scientific Reports, 2023
Rare individuals with Bombay and para-Bombay phenotypes lack or have weak expression of the ABO(H) antigens on surface of red blood cells due to no or very weak H-type α(1,2)fucosyltransferase activity encoded by FUT1.
Mikiko Soejima, Yoshiro Koda
doaj   +1 more source

Estimation of Lewis Blood Group Status by Fluorescence Melting Curve Analysis in Simultaneous Genotyping of c.385A>T and Fusion Gene in FUT2 and c.59T>G and c.314C>T in FUT3

Diagnostics, 2023
Lewis blood group status is determined by two fucosyltransferase activities: those of FUT2-encoded fucosyltransferase (Se enzyme) and FUT3-encoded fucosyltransferase (Le enzyme).
Mikiko Soejima, Yoshiro Koda
doaj   +1 more source

Evaluation of the Correlation between the Alteration of Specific Biochemical Indicators levels in the Early Stages of Colorectal Cancer

مجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Colorectal cancer is one of the most common cancers and considered to be leading causes of cancer death in the world. One of the problems with this type of cancer is its inability to be detected in early stage.
Roya Abbasinatajomrani, Durdi Qujeq, Reza Hajihosseini, Vahid Hosseini   +3 more
doaj  

The Arabidopsis O-fucosyltransferase SPINDLY regulates root hair patterning independently of gibberellin signaling

Development, 2020
Root hairs are able to sense soil composition and play an important role in water and nutrient uptake. In Arabidopsis thaliana, root hairs are distributed in the epidermis in a specific pattern, regularly alternating with non-root hair cells in ...
K. V. Mutanwad, Isabella Zangl, D. Lucyshyn   +2 more
semanticscholar   +1 more source

Subcellular localisation of cerebral fucosyltransferase [PDF]

FEBS Letters, 1984
GDP‐fucose : asialofetuin fucosyltransferase from sheep brain was fractionated on a sucrose gradient into two activity peaks. Using purification on Ficoll adapted from the proposed method [(1980) J. Neurochem. 35, 281‐296], double localisation of cerebral fucosyltransferase was confirmed and the subcellular active fractions identified as light ...
Broquet, P., Serres-Guillaumond, M., Baubichon-Cortay, H., Peschard, Mj, Louisot, P.   +4 more
openaire   +3 more sources