Assessing DNA methylation in the developing human intestinal epithelium: potential link to inflammatory bowel disease. [PDF]
, 2015 DNA methylation is one of the major epigenetic mechanisms implicated in regulating cellular development and cell-type-specific gene expression. Here we performed simultaneous genome-wide DNA methylation and gene expression analysis on purified intestinal
Cario, E +9 more
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Targeting Selectins and Their Ligands in Cancer
Frontiers in Oncology, 2016 Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids have been linked to increased immune cell evasion, drug evasion ...
Alessandro eNatoni +3 more
doaj +1 more source
α1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with β1,4galactosyltransferase I in the Golgi apparatus and monensin-induced swollen vesicles [PDF]
, 2017 The major α1,3fucosyltransferase activity in plasma, liver, and kidney is related to fucosyltransferase VI which is encoded by the FUT6 gene. Here we demonstrate the presence of α1,3fucosyltransferase VI (α3-FucT VI) in the human HepG2 hepatoma cell line
Berger, Eric G. +3 more
core
Veterinary Research, 2011 The mucus layer in the gastrointestinal (GI) tract is considered to be the first line of defense to the external environment. Alteration in mucus components has been reported to occur during intestinal nematode infection in ruminants, but the role of ...
Rinaldi Manuela +8 more
doaj +1 more source
A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy. [PDF]
, 2014 To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Blank, Dennis +18 more
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Glycomic Analysis of Biomedically Important O-glycoconjugates
, 2011 It has been established that all cells carry an array of glycans attached to proteins and lipids that are crucial in the interaction between cells and the surrounding matrix. Proteins are mainly glycosylated on asparagines (N-glycosylation) and serine or
Ismail, Mohd Nazri, Ismail, Mohd Nazri
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An expanded proteomic survey of the human parasite Leishmania major focusing on changes in null mutants of the Golgi GDP-Mannose/Fucose/Arabino pyranose transporter LPG2 or the mitochondrial fucosyltransferase FUT1 [PDF]
, 2022 Gloria Polanco +3 more
openalex +1 more source
The expanding roles of the Sda/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2 [PDF]
, 2014 Background The histo-blood group antigens are carbohydrate structures present in tissues and body fluids, which contribute to the definition of the individual immunophenotype. One of these, the Sda antigen, is expressed on the surface of erythrocytes and
Chiricolo, M. +4 more
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B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen [PDF]
, 2018 Analysis of non-Gal antibody induced after pig-to-baboon cardiac xenotransplantation identified the glycan produced by porcine beta-1,4-N-acetyl-galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen.
Ahmad-Villiers, S +3 more
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