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Recent Research on Fumonisins: A Review
Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 2012Fumonisins are well known mycotoxins produced by Fusarium verticillioides, F. proliferatum and other Fusarium species. Many new fumonisins and fumonisin-like compounds have been detected by mass spectrometry in cultures of F. verticillioides. Recently, fumonisins B(2) and B(4) were produced by Aspergillus niger isolated from coffee and fumonisin B(2 ...
P M Scott
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Determination of fumonisins in milk
Journal of Environmental Science and Health, Part B, 1994Fumonisin B1 (FB1) and fumonisin B2 (FB2) were determined in milk by liquid chromatography (LC) following immunoaffinity column cleanup. Recoveries from milk spiked with 5-50 ng each fumonisin/ml averaged 79-109%. The aminopentol hydrolysis product of FB1 (AP1) was determined by LC after cleanup on a C18 solid phase phase extraction column; mean ...
P M, Scott +4 more
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Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002Sphingoid bases are growth inhibitory and pro-apoptotic for many types of cells when added to cells exogenously, and can be elevated to toxic amounts endogenously when cells are exposed to inhibitors of ceramide synthase. An important category of naturally occurring inhibitors are the fumonisins, which inhibit ceramide synthase through structural ...
Kena, Desai +9 more
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Analysis of heat-processed corn foods for fumonisins and bound fumonisins
Food Additives and Contaminants, 2004Thirty retail samples of heat-processed corn foods, i.e. corn flakes, corn-based breakfast cereals, tortilla chips and corn chips, were analysed for fumonisins--fumonisin B1 (FB1), fumonisin B2 (FB2) and hydrolysed FB1 (HFB1)--as well as for protein- and total-bound FB1. Bound (hidden) fumonisins cannot be detected by conventional analysis.
J W, Park +3 more
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2000
Abstract FB1 in corn-based feeds causes equine leukoencephalomalacia (ELEM) (6,10,19), a disease observed worldwide in horses, donkeys, and mules. ELEM has been recognized for more than a century in corn-growing regions of North America.
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Abstract FB1 in corn-based feeds causes equine leukoencephalomalacia (ELEM) (6,10,19), a disease observed worldwide in horses, donkeys, and mules. ELEM has been recognized for more than a century in corn-growing regions of North America.
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Annals of Tropical Paediatrics, 1998
Fumonisins are mycotoxins produced by Fusarium moniliforme that are prevalent in corn, sorghum, millet and other agricultural products. It is possible that fumonisins are aetiological agents in human oesophageal cancers. The International Agency for Research on Cancer have designated toxins derived from F. moniliforme as group 2B (possibly carcinogenic
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Fumonisins are mycotoxins produced by Fusarium moniliforme that are prevalent in corn, sorghum, millet and other agricultural products. It is possible that fumonisins are aetiological agents in human oesophageal cancers. The International Agency for Research on Cancer have designated toxins derived from F. moniliforme as group 2B (possibly carcinogenic
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Mycotoxin Research, 2001
It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder +4 more
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It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder +4 more
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European Food Research and Technology, 2001
Fumonisins are synthesized by different species of the genus Fusarium but the most significant producers are Fusarium moniliforme and Fusarium proliferatum. The fumonisins belong to the most important toxic fungal metabolites. Maize and maize products are mainly contaminated.
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Fumonisins are synthesized by different species of the genus Fusarium but the most significant producers are Fusarium moniliforme and Fusarium proliferatum. The fumonisins belong to the most important toxic fungal metabolites. Maize and maize products are mainly contaminated.
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Fumonisin mycotoxins in human hair
Biomarkers, 2003This study shows for the first time the accumulation of fumonisin mycotoxins in human hair of population clusters exposed to contaminated maize, and thus the feasibility of human hair analysis for the assessment of past fumonisin exposure. Composite hair samples were obtained from the Bizana, Butterworth and Centane districts within the Transkei region
Vikash, Sewram +3 more
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Fumonisin Toxicity and Metabolism Studies at the USDA
1996Fumonisins are responsible for many of the toxic effects of the common corn fungus, Fusarium moniliforme. They are acute renal and liver toxins in rats, and have tumor promoting activity. Fumonisin B1 is poorly absorbed, rapidly excreted, and persists in small amounts in the liver and kidney. Fumonisins are specific inhibitors of ceramide synthase, and
W P, Norred +3 more
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