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Targeting Fumonisin Biosynthetic Genes
2016The fungus Fusarium is an agricultural problem because it can cause disease on most crop plants and can contaminate crops with mycotoxins. There is considerable variation in the presence/absence and genomic location of gene clusters responsible for synthesis of mycotoxins and other secondary metabolites among species of Fusarium.
Robert H, Proctor, Martha M, Vaughan
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Mycotoxin Research, 2001
It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder +4 more
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It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder +4 more
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Fumonisin intake of the German consumer
Mycotoxin Research, 2008In order to calculate the dietary fumonisin intake of the German consumer, a large survey was carried out on a variety of potentially contaminated products in the period between December 1998 and July 2001. A total of 1960 food samples comprising all known relevant groups of products were analysed for fumonisins.
I, Zimmer +8 more
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Fumonisin Toxicity and Sphingolipid Biosynthesis
1996Fumonisins are inhibitors of sphinganine (sphingosine) N-acyltransferase (ceramide synthase) in vitro, and exhibit competitive-type inhibition with respect to both substrates of this enzyme (sphinganine and fatty acyl-CoA). Removal of the tricarballylic acids from fumonisin B1 reduces the potency by at least 10 fold; and fumonisin A1 (which is ...
A H, Merrill +11 more
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1996
Occurrence of Fumonisins in Foods and Feeds: Fumonisins: History, Worldwide Occurrence and Impact W.F.O. Marasas Occurrence of Fumonisins in the US Food Supply A.E. Pohland Occurrence of Fusarium and Fumonisins on Food Grains and in Foods L.B. Bullerman Occurrence and Fate of Fumonisins in Beef J.S. Smith, R.A.
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Occurrence of Fumonisins in Foods and Feeds: Fumonisins: History, Worldwide Occurrence and Impact W.F.O. Marasas Occurrence of Fumonisins in the US Food Supply A.E. Pohland Occurrence of Fusarium and Fumonisins on Food Grains and in Foods L.B. Bullerman Occurrence and Fate of Fumonisins in Beef J.S. Smith, R.A.
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Occurrence and Fate of Fumonisins in Beef
1996For 30 days, two groups of three steers each were fed a diet of herd-mix and alfalfa hay (control) or the diet with part of the herd-mix replaced by corn grits contaminated with 400 micrograms/g FB1 and 130 micrograms/g FB2. Premortem examination involved liver functionality tests; serum analyses for AST, GGT, LDH, cholesterol, and total bilirubin ...
J S, Smith, R A, Thakur
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Chromatographic determination of the fumonisin mycotoxins
Journal of Chromatography A, 1998The fumonisins are a recently identified group of fungal toxins, occurring worldwide in naturally contaminated maize, which have elicited considerable attention over the past decade due to their association with the animal disease syndromes, equine leukoencephalomalacia and porcine pulmonary oedema, and their reported association with oesophageal ...
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