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Fumonisins

International Journal of Food Microbiology, 1993
Fusarium moniliforme Sheldon is a common fungal contaminant of corn and produces a variety of mycotoxins. Among these are the recently discovered fumonisins, which are now known to cause certain animal diseases, namely leukoencephalomalacia in horses and pulmonary edema in swine.
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Determination of fumonisins in milk

Journal of Environmental Science and Health, Part B, 1994
Fumonisin B1 (FB1) and fumonisin B2 (FB2) were determined in milk by liquid chromatography (LC) following immunoaffinity column cleanup. Recoveries from milk spiked with 5-50 ng each fumonisin/ml averaged 79-109%. The aminopentol hydrolysis product of FB1 (AP1) was determined by LC after cleanup on a C18 solid phase phase extraction column; mean ...
P M, Scott   +4 more
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Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Sphingoid bases are growth inhibitory and pro-apoptotic for many types of cells when added to cells exogenously, and can be elevated to toxic amounts endogenously when cells are exposed to inhibitors of ceramide synthase. An important category of naturally occurring inhibitors are the fumonisins, which inhibit ceramide synthase through structural ...
Kena, Desai   +9 more
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Analysis of heat-processed corn foods for fumonisins and bound fumonisins

Food Additives and Contaminants, 2004
Thirty retail samples of heat-processed corn foods, i.e. corn flakes, corn-based breakfast cereals, tortilla chips and corn chips, were analysed for fumonisins--fumonisin B1 (FB1), fumonisin B2 (FB2) and hydrolysed FB1 (HFB1)--as well as for protein- and total-bound FB1. Bound (hidden) fumonisins cannot be detected by conventional analysis.
J W, Park   +3 more
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Recent research on fumonisins: a review

Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 2012
Fumonisins are well known mycotoxins produced by Fusarium verticillioides, F. proliferatum and other Fusarium species. Many new fumonisins and fumonisin-like compounds have been detected by mass spectrometry in cultures of F. verticillioides. Recently, fumonisins B(2) and B(4) were produced by Aspergillus niger isolated from coffee and fumonisin B(2 ...
P M Scott
exaly   +3 more sources

Fumonisins and human health

Annals of Tropical Paediatrics, 1998
Fumonisins are mycotoxins produced by Fusarium moniliforme that are prevalent in corn, sorghum, millet and other agricultural products. It is possible that fumonisins are aetiological agents in human oesophageal cancers. The International Agency for Research on Cancer have designated toxins derived from F. moniliforme as group 2B (possibly carcinogenic
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Fumonisin

2000
Abstract FB1 in corn-based feeds causes equine leukoencephalomalacia (ELEM) (6,10,19), a disease observed worldwide in horses, donkeys, and mules. ELEM has been recognized for more than a century in corn-growing regions of North America.
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Foods and fumonisins

European Food Research and Technology, 2001
Fumonisins are synthesized by different species of the genus Fusarium but the most significant producers are Fusarium moniliforme and Fusarium proliferatum. The fumonisins belong to the most important toxic fungal metabolites. Maize and maize products are mainly contaminated.
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Fumonisin Toxicity and Metabolism Studies at the USDA

1996
Fumonisins are responsible for many of the toxic effects of the common corn fungus, Fusarium moniliforme. They are acute renal and liver toxins in rats, and have tumor promoting activity. Fumonisin B1 is poorly absorbed, rapidly excreted, and persists in small amounts in the liver and kidney. Fumonisins are specific inhibitors of ceramide synthase, and
W P, Norred   +3 more
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Immunochemical Methods for Fumonisins

1996
Both monoclonal and polyclonal antibodies have been raised against fumonisins (Fm) and the hydrolyzed toxin in several laboratories. They have been used in several immunoassays and can detect 5 to 5000 ng of FmB1/mL in a "clean" standard solution. However, sample matrices still give severe interferences.
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