Results 171 to 180 of about 7,201 (216)

Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Sphingoid bases are growth inhibitory and pro-apoptotic for many types of cells when added to cells exogenously, and can be elevated to toxic amounts endogenously when cells are exposed to inhibitors of ceramide synthase. An important category of naturally occurring inhibitors are the fumonisins, which inhibit ceramide synthase through structural ...
Kena, Desai, M Cameron, Sullards, Jeremy, Allegood, Elaine, Wang, Eva M, Schmelz, Michaela, Hartl, Hans-Ulrich, Humpf, D C, Liotta, Qiong, Peng, Alfred H, Merrill   +9 more
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Analysis of heat-processed corn foods for fumonisins and bound fumonisins

Food Additives and Contaminants, 2004
Thirty retail samples of heat-processed corn foods, i.e. corn flakes, corn-based breakfast cereals, tortilla chips and corn chips, were analysed for fumonisins--fumonisin B1 (FB1), fumonisin B2 (FB2) and hydrolysed FB1 (HFB1)--as well as for protein- and total-bound FB1. Bound (hidden) fumonisins cannot be detected by conventional analysis.
J W, Park, P M, Scott, B P Y, Lau, D A, Lewis   +3 more
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Fumonisins and human health

Annals of Tropical Paediatrics, 1998
Fumonisins are mycotoxins produced by Fusarium moniliforme that are prevalent in corn, sorghum, millet and other agricultural products. It is possible that fumonisins are aetiological agents in human oesophageal cancers. The International Agency for Research on Cancer have designated toxins derived from F. moniliforme as group 2B (possibly carcinogenic
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Fumonisin

2000
Abstract FB1 in corn-based feeds causes equine leukoencephalomalacia (ELEM) (6,10,19), a disease observed worldwide in horses, donkeys, and mules. ELEM has been recognized for more than a century in corn-growing regions of North America.
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Foods and fumonisins

European Food Research and Technology, 2001
Fumonisins are synthesized by different species of the genus Fusarium but the most significant producers are Fusarium moniliforme and Fusarium proliferatum. The fumonisins belong to the most important toxic fungal metabolites. Maize and maize products are mainly contaminated.
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Fumonisin Toxicity and Metabolism Studies at the USDA

1996
Fumonisins are responsible for many of the toxic effects of the common corn fungus, Fusarium moniliforme. They are acute renal and liver toxins in rats, and have tumor promoting activity. Fumonisin B1 is poorly absorbed, rapidly excreted, and persists in small amounts in the liver and kidney. Fumonisins are specific inhibitors of ceramide synthase, and
W P, Norred, K A, Voss, R T, Riley, R D, Plattner   +3 more
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Induction of apoptosis in cultured human proximal tubule cells by fumonisins and fumonisin metabolites

Mycotoxin Research, 2001
It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder, H-U, Humpf, G, Schwerdt, R, Freudinger, M, Gekle   +4 more
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Immunochemical Methods for Fumonisins

1996
Both monoclonal and polyclonal antibodies have been raised against fumonisins (Fm) and the hydrolyzed toxin in several laboratories. They have been used in several immunoassays and can detect 5 to 5000 ng of FmB1/mL in a "clean" standard solution. However, sample matrices still give severe interferences.
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Targeting Fumonisin Biosynthetic Genes

2016
The fungus Fusarium is an agricultural problem because it can cause disease on most crop plants and can contaminate crops with mycotoxins. There is considerable variation in the presence/absence and genomic location of gene clusters responsible for synthesis of mycotoxins and other secondary metabolites among species of Fusarium.
Robert H, Proctor, Martha M, Vaughan
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Fumonisin intake of the German consumer

Mycotoxin Research, 2008
In order to calculate the dietary fumonisin intake of the German consumer, a large survey was carried out on a variety of potentially contaminated products in the period between December 1998 and July 2001. A total of 1960 food samples comprising all known relevant groups of products were analysed for fumonisins.
I, Zimmer, E, Usleber, H, Klaffke, R, Weber, P, Majerus, H, Otteneder, M, Gareis, R, Dietrich, E, Märtlbauer   +8 more
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