Results 161 to 170 of about 3,632,451 (277)

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation. [PDF]

Chem Sci, 2022
Nagaraj M, Najarzadeh Z, Pansieri J, Biverstål H, Musteikyte G, Smirnovas V, Matthews S, Emanuelsson C, Johansson J, Buxbaum JN, Morozova-Roche L, Otzen DE.   +11 more
europepmc   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid. [PDF]

Proc Natl Acad Sci U S A, 2021
Salinas N, Tayeb-Fligelman E, Sammito MD, Bloch D, Jelinek R, Noy D, Usón I, Landau M.   +7 more
europepmc   +1 more source

Altered Brain Extracellular Matrix Structure and Sex-Specific Learning/Memory Dysfunction in Mice Lacking the Functional Amyloid Cystatin-Related Epididymal Spermatogenic. [PDF]

eNeuro
Gomez A, Logsdon AF, Bailoo JD, Cornwall GA.   +3 more
europepmc   +1 more source

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

Advanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu, Pengfei Yang, Meng Li, Zichen Cao, Tian Lan, Yan Zhang, Weibiao Zhou, Lianzhou Jiang, Xiaonan Sui   +8 more
wiley   +1 more source

Amelogenin proteolysis orchestrates functional amyloid pathways in enamel development. [PDF]

Matrix Biol
de Sousa ET, Ackerman L, Bonde JS, Habelitz S, Bai Y.   +4 more
europepmc   +1 more source

The intrinsically disordered region of the human parathyroid hormone controls functional amyloid properties. [PDF]

J Biol Chem
Sachan S, Bhatia T, Baumann M, Weber M, Gordijenko I, Voigt B, Ott M, Balbach J.   +7 more
europepmc   +1 more source

Amyloid‐Guided Assembly of Magnetically Recyclable Enzymatic Nanofibers Toward Sustainable Biocatalysis

Advanced Science, EarlyView.
A hierarchical strategy integrates linker engineering, amyloid‐guided self‐assembly, and magnetic immobilization to construct recyclable DPAO4‐DMAO7 enzymatic nanofibers. The resulting magnetic composites enable biogenic amine conversion in complex food matrices and simulated wastewater, while rapid magnetic separation supports repeated reuse. The work
Shuangping Liu, Qilin Yang, Qian Zhang, Tiantian Liu, Xiao Han, Jian Mao   +5 more
wiley   +1 more source

DNA Modulates Structural Transitions and Oligomerization Kinetics of the Functional Amyloid CRES. [PDF]

J Am Chem Soc
Kukreja R, Canny MD, Cornwall GA, Latham MP.   +3 more
europepmc   +1 more source