Results 11 to 20 of about 11,568 (285)
Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics [PDF]
Nature Communications, 2023 Antibiotic resistance of bacteria is considered one of the most alarming developments in modern medicine. While varied pathways for bacteria acquiring antibiotic resistance have been identified, there still are open questions concerning the mechanisms ...
Elad Arad +9 more
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Beyond One-Trick Ponies: The Multifunctional Marvels of Microbial Functional Amyloids [PDF]
Microorganisms, 2023 Various organisms, including bacteria, protists, fungi, plants, and animals, secrete proteins and peptides that self-assemble into ordered amyloid fibrils that perform different physiological functions [...]
Meytal Landau
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Functional amyloids in bacteria [PDF]
International microbiology : the official journal of the Spanish Society for Microbiology, 2014 The term amyloidosis is used to refer to a family of pathologies altering the homeostasis of human organs. Despite having a name that alludes to starch content, the amyloid accumulations are made up of proteins that polymerize as long and rigid fibers ...
Diego Romero, Roberto Kolter
core +4 more sources
The Role of Functional Amyloids in Multicellular Growth and Development of Gram-Positive Bacteria. [PDF]
Biomolecules, 2017 Amyloid fibrils play pivotal roles in all domains of life. In bacteria, these fibrillar structures are often part of an extracellular matrix that surrounds the producing organism and thereby provides protection to harsh environmental conditions. Here, we
Dragoš A, Kovács ÁT, Claessen D.
europepmc +6 more sources
Functional Amyloids in Adhesion of Non-albicans Candida Species [PDF]
PathogensCandida fungal species are the most common fungal opportunistic pathogens. Their ability to form antifungal resistant biofilms contributes to their increasing clinical frequency.
Melissa C. Garcia-Sherman +4 more
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Fold modulating function: Bacterial toxins to functional amyloids [PDF]
Frontiers in Microbiology, 2014 Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is well known that environmental factors control toxin expression, however recent work suggests that some bacteria manipulate the fold of these protein toxins ...
Adnan Khawaja Syed, Blaise R Boles
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Bacterial functional amyloids: Order from disorder. [PDF]
Biochim Biophys Acta Proteins Proteom, 2019 The discovery of intrinsic disorderness in proteins and peptide regions has given a new and useful insight into the working of biological systems. Due to enormous plasticity and heterogeneity, intrinsically disordered proteins or regions in proteins can perform myriad of functions.
Jain N, Chapman MR.
europepmc +4 more sources
Evolutionary insight into the functional amyloids of the pseudomonads. [PDF]
PLoS ONE, 2013 Functional bacterial amyloids (FuBA) are important components in many environmental biofilms where they provide structural integrity to the biofilm, mediate bacterial aggregation and may function as virulence factor by binding specifically to host cell ...
Morten S Dueholm +2 more
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The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid [PDF]
Advanced ScienceAmyloids, once viewed solely as pathological hallmarks, are now recognized as widespread and versatile functional protein assemblies. Bacterial functional amyloids (FuBAs), particularly curli (CsgA) from Escherichia coli and FapC from Pseudomonas, have ...
Samuel Peña‐Díaz +12 more
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Peptide detection of fungal functional amyloids in infected tissue. [PDF]
PLoS ONE, 2014 Many fungal cell adhesion proteins form functional amyloid patches on the surface of adhering cells. The Candida albicans Agglutinin-like sequence (Als) adhesins are exemplars for this phenomenon, and have amyloid forming sequences that are conserved ...
Melissa C Garcia-Sherman +6 more
doaj +2 more sources