Results 41 to 50 of about 11,624 (280)
Oat Plant Amyloids for Sustainable Functional Materials
Advanced Science, 2022 Amyloid functional materials from amyloid fibril building blocks, produced in vitro from amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging from environmental science and biomedicine, to nanotechnology and ...
Jiangtao Zhou +7 more
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Functional Amyloids Signal Their Arrival [PDF]
Science Signaling, 2009 Several peptide and protein hormones are stored in an amyloid configuration in secretory granules.
Matthew P, Badtke +2 more
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“What Doesn’t Kill You Makes You Stronger”: Future Applications of Amyloid Aggregates in Biomedicine
Molecules, 2020 Amyloid proteins are linked to the pathogenesis of several diseases including Alzheimer’s disease, but at the same time a range of functional amyloids are physiologically important in humans.
Sherin Abdelrahman +5 more
doaj +1 more source
The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils
Nature Communications, 2022 In this work the authors provide high-resolution structural support for the amyloid-antimicrobial link via functional amyloids displaying propeller-like and kinked cross-β fibrils.
Robert Bücker +6 more
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Amyloid and the origin of life : self-replicating catalytic amyloids as prebiotic informational and protometabolic entities [PDF]
, 2018 A crucial stage in the origin of life was the emergence of the first molecular entity that was able to replicate, transmit information, and evolve on the early Earth. The amyloid world hypothesis posits that in the pre-RNA era, information processing was
Maury, Carl Peter J.
core +1 more source
An Amyloid Organelle: Solid State NMR Evidence for Cross-Beta Assembly of Gas Vesicles [PDF]
, 2011 Functional amyloids have been identified in a wide range of organisms, taking on a variety of biological roles and being controlled by remarkable mechanisms of directed assembly.
Bayro +35 more
core +1 more source
AmyPro: a database of proteins with validated amyloidogenic regions [PDF]
, 2017 Soluble functional proteins may transform into insoluble amyloid fibrils that deposit in a variety of tissues. Amyloid formation is a hallmark of age-related degenerative disorders.
De Baets, G. +4 more
core +1 more source
Good Amyloid, Bad Amyloid-What's the Difference? [PDF]
PLoS Biology, 2016 Why do some amyloids cause serious neurodegenerative diseases, while others have important biological functions? A new study of the functional amyloid Orb2 suggests that it's all about speed. Read the Research Article.
Roland G Roberts
doaj +1 more source
Blessings in disguise: biological benefits of prion-like mechanisms [PDF]
, 2013 Prions and amyloids are often associated with disease, but related mechanisms provide beneficial functions in nature. Prion-like mechanisms (PriLiMs) are found from bacteria to humans, where they alter the biological and physical properties of prion-like
Lindquist, Susan, Newby, Gregory Arthur
core +1 more source
Prion, 2010 Evidence is growing at an increasing -pace that amyloid fibers are not just the result of aberrant protein folding associated with neurodegenerative diseases, but are widespread in nature for beneficial reasons. Amyloid is an attractive building material because its robust design and simple repetitive structure make for very durable and metabolically ...
openaire +3 more sources