Bacterial functional amyloids: Order from disorder. [PDF]
Biochim Biophys Acta Proteins Proteom, 2019 The discovery of intrinsic disorderness in proteins and peptide regions has given a new and useful insight into the working of biological systems. Due to enormous plasticity and heterogeneity, intrinsically disordered proteins or regions in proteins can perform myriad of functions.
Jain N, Chapman MR.
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Cold Spring Harb Perspect Biol, 2019 When protein/peptides aggregate, they usually form the amyloid state consisting of cross β-sheet structure built by repetitively stacked β-strands forming long fibrils. Amyloids are usually associated with disease including Alzheimer's. However, amyloid has many useful features.
Otzen D, Riek R.
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Functional Amyloids in Reproduction. [PDF]
Biomolecules, 2017 Amyloids are traditionally considered pathological protein aggregates that play causative roles in neurodegenerative disease, diabetes and prionopathies. However, increasing evidence indicates that in many biological systems nonpathological amyloids are formed for functional purposes.
Hewetson A +6 more
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A simplified exactly solvable model for beta-amyloid aggregation
, 2010 We propose an exactly solvable simplified statistical mechanical model for the thermodynamics of beta-amyloid aggregation, generalizing a well-studied model for protein folding.
Maritan, Amos +2 more
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Remediation of Metal Oxide Nanotoxicity with a Functional Amyloid
Advanced ScienceUnderstanding the environmental health and safety of nanomaterials (NanoEHS) is essential for the sustained development of nanotechnology. Although extensive research over the past two decades has elucidated the phenomena, mechanisms, and implications of
Yue Wang +10 more
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Enhanced purification coupled with biophysical analyses shows cross-β structure as a core building block for Streptococcus mutans functional amyloids. [PDF]
Sci Rep, 2020 Barran-Berdon AL +11 more
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Dynamic visualization of extracellular matrix components in <i>S. aureus</i> colony biofilms reveals functional amyloids leading to the formation of cap-like structures. [PDF]
BiofilmZhang T +11 more
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Functional amyloids promote retention of public goods in bacteria. [PDF]
Proc Biol Sci, 2019 Bruce JB, West SA, Griffin AS.
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Ecology and Biogenesis of Functional Amyloids in Pseudomonas. [PDF]
J Mol Biol, 2018 Rouse SL, Matthews SJ, Dueholm MS.
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Microbial functional amyloids serve diverse purposes for structure, adhesion and defence. [PDF]
Biophys Rev, 2019 Shanmugam N +5 more
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