The Tubular Sheaths Encasing Methanosaeta thermophila Filaments Are Functional Amyloids* [PDF]
Journal of Biological Chemistry, 2015 Archaea are renowned for their ability to thrive in extreme environments, although they can be found in virtually all habitats. Their adaptive success is linked to their unique cell envelopes that are extremely resistant to chemical and thermal ...
Daniel Otzen +2 more
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Functional Amyloids Keep Quorum-sensing Molecules in Check* [PDF]
Journal of Biological Chemistry, 2015 The mechanism by which extracellular metabolites, including redox mediators and quorum-sensing signaling molecules, traffic through the extracellular matrix of biofilms is poorly explored.
Michael Givskov +2 more
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Multifunctional Amyloids in the Biology of Gram-Positive Bacteria
Microorganisms, 2020 Since they were discovered, amyloids have proven to be versatile proteins able to participate in a variety of cellular functions across all kingdoms of life.
Ana Álvarez-Mena +3 more
doaj +2 more sources
Direct Identification of Functional Amyloid Proteins by Label-Free Quantitative Mass Spectrometry
Biomolecules, 2017 Functional amyloids are important structural and functional components of many biofilms, yet our knowledge of these fascinating polymers is limited to a few examples for which the native amyloids have been isolated in pure form.
Heidi N. Danielsen +6 more
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Evolutionary insight into the functional amyloids of the pseudomonads. [PDF]
PLoS ONE, 2013 Functional bacterial amyloids (FuBA) are important components in many environmental biofilms where they provide structural integrity to the biofilm, mediate bacterial aggregation and may function as virulence factor by binding specifically to host cell ...
Morten S Dueholm +2 more
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Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma [PDF]
Biology, 2016 In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative disease. At the beginning
Martin L. Daus
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Recent Advances in Amyloids Structural Studies and Thin Film Applications
MoleculesAmyloids are protein-based biomaterials composed of fibrils with cross-β cores. Previously only associated with degenerative diseases, such as Parkinson’s disease, Alzheimer’s disease, and diabetes, amyloids remain active and functional both in vivo and ...
Eugenia Pechkova +3 more
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Peptide detection of fungal functional amyloids in infected tissue. [PDF]
PLoS ONE, 2014 Many fungal cell adhesion proteins form functional amyloid patches on the surface of adhering cells. The Candida albicans Agglutinin-like sequence (Als) adhesins are exemplars for this phenomenon, and have amyloid forming sequences that are conserved ...
Melissa C Garcia-Sherman +6 more
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New insight into the molecular control of bacterial functional amyloids [PDF]
Frontiers in Cellular and Infection Microbiology, 2015 Amyloid protein structure has been discovered in a variety of functional or pathogenic contexts. What distinguishes the former from the latter is that functional amyloid systems possess dedicated molecular control systems that determine the timing ...
Stephen eMatthews, Jonathan eTaylor
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Functional Amyloids in Reproduction. [PDF]
Biomolecules, 2017 Amyloids are traditionally considered pathological protein aggregates that play causative roles in neurodegenerative disease, diabetes and prionopathies.
Hewetson A +6 more
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