Results 21 to 30 of about 11,568 (285)

SynBio and the Boundaries between Functional and Pathogenic RepA-WH1 Bacterial Amyloids

open access: yesmSystems, 2020
Amyloids are protein polymers that were initially linked to human diseases. Across the whole Tree of Life, many disease-unrelated proteins are now emerging for which amyloids represent distinct functional states.
Rafael Giraldo
doaj   +3 more sources

Search and Identification of Amyloid Proteins

open access: yesMethods and Protocols, 2023
Amyloids are fibrillar proteins with a cross-β structure. Pathological amyloids are associated with the development of a number of incurable diseases, while functional amyloids regulate vital processes. The detection of unknown amyloids in living objects
Tatyana A. Belashova   +5 more
doaj   +1 more source

Multifunctional Amyloids in the Biology of Gram-Positive Bacteria

open access: yesMicroorganisms, 2020
Since they were discovered, amyloids have proven to be versatile proteins able to participate in a variety of cellular functions across all kingdoms of life.
Ana Álvarez-Mena   +3 more
doaj   +1 more source

Purification of the Bacterial Amyloid “Curli” from Salmonella enterica Serovar Typhimurium and Detection of Curli from Infected Host Tissues

open access: yesBio-Protocol, 2022
Microbiologists are learning to appreciate the importance of “functional amyloids” that are produced by numerous bacterial species and have impacts beyond the microbial world. These structures are used by bacteria to link together, presumably to increase
Murugesan Sivaranjani   +5 more
doaj   +1 more source

Zinc–dysprosium functionalized amyloid fibrils [PDF]

open access: yesDalton Transactions, 2019
The heterometallic Zn2Dy2 entity bearing partially saturated metal centres covalently decorates a highly ordered amyloid fibril core and the functionalised assembly exhibits catalytic Lewis acid behaviour.
Stavroula I. Sampani   +4 more
openaire   +3 more sources

Amyloids: The History of Toxicity and Functionality

open access: yesBiology, 2021
Proteins can perform their specific function due to their molecular structure. Partial or complete unfolding of the polypeptide chain may lead to the misfolding and aggregation of proteins in turn, resulting in the formation of different structures such ...
Elmira I. Yakupova   +4 more
doaj   +1 more source

Amyloid prions in fungi [PDF]

open access: yes, 2016
Prions are infectious protein polymers that have been found to cause fatal diseases in mammals. Prions have also been identified in fungi (yeast and filamentous fungi), where they behave as cytoplasmic non-Mendelian genetic elements.
Aguzzi   +122 more
core   +2 more sources

Unzipping a Functional Microbial Amyloid [PDF]

open access: yesACS Nano, 2012
Bacterial and fungal species produce some of the best-characterized functional amyloids, that is, extracellular fibres that play key roles in mediating adhesion and biofilm formation. Yet, the molecular details underlying their mechanical strength remain poorly understood.
David, Alsteens   +3 more
openaire   +2 more sources

Direct Identification of Functional Amyloid Proteins by Label-Free Quantitative Mass Spectrometry

open access: yesBiomolecules, 2017
Functional amyloids are important structural and functional components of many biofilms, yet our knowledge of these fascinating polymers is limited to a few examples for which the native amyloids have been isolated in pure form.
Heidi N. Danielsen   +6 more
doaj   +1 more source

Oat Plant Amyloids for Sustainable Functional Materials

open access: yesAdvanced Science, 2022
Amyloid functional materials from amyloid fibril building blocks, produced in vitro from amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging from environmental science and biomedicine, to nanotechnology and ...
Jiangtao Zhou   +7 more
doaj   +1 more source

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