Functions of fungal melanin beyond virulence. [PDF]
Fungal Biol Rev, 2017 Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in microbial pathogenesis is well established; however, these complex biomolecules also confer upon fungal microorganisms the faculty to tolerate extreme environments such as the Earth's poles, the International Space Station and places contaminated by toxic ...
Cordero RJ, Casadevall A.
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Synthesis and assembly of fungal melanin [PDF]
Applied Microbiology and Biotechnology, 2011 Melanin is a unique pigment with myriad functions that is found in all biological kingdoms. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. Melanin contributes to the ability of fungi to survive in harsh environments.
Helene C, Eisenman, Arturo, Casadevall
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Fungal Melanins and Applications in Healthcare, Bioremediation and Industry [PDF]
Journal of Fungi, 2021 Melanin is a complex multifunctional pigment found in all kingdoms of life, including fungi. The complex chemical structure of fungal melanins, yet to be fully elucidated, lends them multiple unique functions ranging from radioprotection and antioxidant ...
Ellie Rose Mattoon +2 more
doaj +3 more sources
Tricyclazole alleviates Fonsecaea pedrosoi-induced immune suppression of neutrophils by inhibiting DHN-melanin biosynthesis [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionChromoblastomycosis (CBM) is a chronic cutaneous infection caused by dematiaceous fungi, characterized by therapeutic challenges such as difficulty in pathogen clearance and high recurrence rates. Fonsecaea pedrosoi (F.
Chunjiao Zheng +8 more
doaj +2 more sources
Fungal melanins differ in planar stacking distances. [PDF]
PLoS ONE, 2012 Melanins are notoriously difficult to study because they are amorphous, insoluble and often associated with other biological materials. Consequently, there is a dearth of structural techniques to study this enigmatic pigment.
Arturo Casadevall +3 more
doaj +4 more sources
Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways [PDF]
Journal of Fungi, 2021 Fungal melanins represent a resource for important breakthroughs in industry and medicine, but the characterization of their composition, synthesis, and structure is not well understood.
Benjamin D. Strycker +7 more
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Synthetic fungal melanin nanoparticles with excellent antioxidative property
Giant, 2022 Melanin-inspired polymers have been widely used in biomedical applications due to their promising biocompatibility and antioxidant capacity. Although several works focusing on the eumelanin-like biomaterials such as polydopamine nanoparticles (PDA NPs) have been well documented, their free radical scavenging capability usually needed to be tailored and
Hengjie Zhang +7 more
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Melanin and Neuromelanin in Humans: Insights Across Health, Aging, Diseases, and Unexpected Aspects of Fungal Melanogenesis [PDF]
BiomoleculesMelanin pigments are ubiquitous biopolymers across diverse life forms and play multifaceted roles in cellular defense and environmental adaptation. The specialized neuromelanin in human brains accumulates mainly within catecholaminergic neurons of the ...
Kathleen Hatch +3 more
doaj +2 more sources
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity. [PDF]
Nat Commun, 2020 Gonçalves SM +33 more
europepmc +2 more sources
A differential genome-wide transcriptome analysis : impact of cellular copper on complex biological processes like aging and development [PDF]
, 2012 The regulation of cellular copper homeostasis is crucial in biology. Impairments lead to severe dysfunctions and are known to affect aging and development.
Grimm, Carolin +3 more
core +9 more sources