Results 21 to 30 of about 11,097 (135)

The role of L-DOPA on melanization and mycelial production in Malassezia furfur. [PDF]

PLoS ONE, 2013
Melanins are synthesized by organisms of all biological kingdoms and comprise a heterogeneous class of natural pigments. Certain of these polymers have been implicated in the pathogenesis of several important human fungal pathogens.
Sirida Youngchim, Joshua D Nosanchuk, Soraya Pornsuwan, Susumu Kajiwara, Nongnuch Vanittanakom   +4 more
doaj   +1 more source

Melaninization Reduces Cryptococcus neoformans Susceptibility to Mechanical Stress

mSphere, 2023
Melanin is a complex pigment that is found in various fungal species and is associated with a multitude of protective functions against environmental stresses.
Ellie Rose Mattoon, Radames J. B. Cordero, Arturo Casadevall   +2 more
doaj   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways

Journal of Fungi, 2021
Fungal melanins represent a resource for important breakthroughs in industry and medicine, but the characterization of their composition, synthesis, and structure is not well understood.
Benjamin D. Strycker, Zehua Han, Aysan Bahari, Tuyetnhu Pham, Xiaorong Lin, Brian D. Shaw, Alexei V. Sokolov, Marlan O. Scully   +7 more
doaj   +1 more source

Characterization of melanin and optimal conditions for pigment production by an endophytic fungus, Spissiomyces endophytica SDBR-CMU319.

PLoS ONE, 2019
Melanin is a natural pigment that is produced by filamentous fungi. In this study, the endophytic species, Spissiomyces endophytica (strain SDBR-CMU319), produced a brown-black pigment in the mycelia.
Nakarin Suwannarach, Jaturong Kumla, Bunta Watanabe, Kenji Matsui, Saisamorn Lumyong   +4 more
doaj   +1 more source

Transposable element insertions shape gene regulation and melanin production in a fungal pathogen of wheat

BMC Biology, 2018
Background Fungal plant pathogens pose major threats to crop yield and sustainable food production if they are highly adapted to their host and the local environment.
Parvathy Krishnan, Lukas Meile, Clémence Plissonneau, Xin Ma, Fanny E. Hartmann, Daniel Croll, Bruce A. McDonald, Andrea Sánchez-Vallet   +7 more
doaj   +1 more source

Solubilized melanin suppresses macrophage function

FEBS Open Bio, 2019
Melanin‐producing Cryptococcus and Aspergillus are highly invasive and can suppress or escape the immune system of the host. Since non‐melanin‐producing strains do not affect the immune system, melanin may play a role in immune system suppression ...
Katsuya Tajima, Daisuke Yamanaka, Ken‐ichi Ishibashi, Yoshiyuki Adachi, Naohito Ohno   +4 more
doaj   +1 more source

Diagnostic utility of melanin production by fungi: Study on tissue sections and culture smears with Masson-Fontana stain

Indian Journal of Pathology and Microbiology, 2014
Background: Dematiaceous fungi appear brown in tissue section due to melanin in their cell walls. When the brown color is not seen on routine H and E and culture is not available, differentiation of dematiaceous fungi from other fungi is difficult on ...
Challa Sundaram, G Uppin Shantveer, Pamidi Umabala, Vemu Lakshmi   +3 more
doaj   +1 more source

Mathematical modeling predicts enhanced growth of X-ray irradiated pigmented fungi. [PDF]

PLoS ONE, 2014
Ionizing radiation is known for its cytotoxic and mutagenic properties. However, recent evidence suggests that chronic sub-lethal irradiation stimulates the growth of melanin-pigmented (melanized) fungi, supporting the hypothesis that interactions ...
Igor Shuryak, Ruth A Bryan, Joshua D Nosanchuk, Ekaterina Dadachova   +3 more
doaj   +1 more source

Galleria mellonella immune melanization is fungicidal during infection

Communications Biology, 2022
Real-time imaging of fungal infection and tissue clearing in the wax moth, Galleria mellonella, help evaluate the role of melanin in the insect host immune response to fungal pathogens.
Daniel F. Q. Smith, Quigly Dragotakes, Madhura Kulkarni, J. Marie Hardwick, Arturo Casadevall   +4 more
doaj   +1 more source