Results 31 to 40 of about 11,097 (135)

Melanin Induction Restores the Pathogenicity of Gaeumannomyces graminis var. tritici in Wheat Plants

open access: yesJournal of Fungi, 2023
One of the most challenging aspects of long-term research based on microorganisms is the maintenance of isolates under ex situ conditions, particularly the conservation of phytopathological characteristics.
Camila Aranda   +7 more
doaj   +1 more source

Characterization of melanin from Exophiala mesophila with the prospect of potential biotechnological applications

open access: yesFrontiers in Fungal Biology
IntroducionFungal melanin is an underexplored natural biomaterial of great biotechnological interest in different areas. This study investigated the physical, chemical, electrochemical, and metal-binding properties of melanin extracted from the ...
Cristy Medina-Armijo   +7 more
doaj   +1 more source

Identification of fungal melanin production and the role of anti-melanin agents

open access: yesPakistan Journal of Pharmaceutical Sciences, 2023
Accumulation of melanin pigment in some specific areas of human skin leads to various skin disorders. This study includes melanin production and extraction from non-dermatophyte, filamentous fungi (Aspergillus niger).
Saba Iqbal, Fatima Ismail
doaj   +1 more source

Extraction and virulence analysis of melanin from Fonsecaea monophora

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG   +8 more
doaj   +1 more source

Melanin's Role in Balancing Mechanical Strength and Reproductive Output in Environmentally Stressed Fungal Spores

open access: yesAdvanced Functional Materials, EarlyView.
Melanin content directly controls fungal spore mechanical properties, with pigmented spores achieving rupture forces two orders of magnitude higher than hyaline spores. Environmental stress drives this quantity‐quality tradeoff; stressed species invest energy in melanin‐reinforced, mechanically superior thick‐walled, super‐hydrophobic spores, while ...
Atul Agrawal, Steven E. Naleway
wiley   +1 more source

Improvement of DOPA-Melanin Production by Aspergillus nidulans Using Eco-Friendly and Inexpensive Substrates

open access: yesJournal of Fungi, 2023
Fungal pigments, including melanin, are recognized as promising materials for biomedical, environmental, and technological applications. In previous studies, we have demonstrated that the DOPA-melanin produced by the MEL1 mutant of Aspergillus nidulans ...
Beatriz Silva Campanhol   +4 more
doaj   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Synthesis and role of melanin for tolerating in vitro rumen digestion in Duddingtonia flagrans, a nematode-trapping fungus

open access: yesMycology, 2019
We describe the synthesis and a function of melanin in Duddingtonia flagrans, a nematode-trapping fungus. We tested various culture media treated with L-DOPA, glucose and tricyclazole on fungal growth and melanin distribution using infrared spectroscopy (
Deivid França Freitas   +8 more
doaj   +1 more source

Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans

open access: yesmBio, 2019
Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal pathogens, but comprehensive regulatory mechanisms remain unidentified.
Dongpil Lee   +6 more
doaj   +1 more source

Melanin in fungi: advances in structure, biosynthesis, regulation, and metabolic engineering

open access: yesMicrobial Cell Factories
Fungi can synthesize a diverse range of melanins with appropriate physicochemical and biological characteristics for numerous applications in health, environmental protection, energy, and industry.
Yanping Qin, Yuxian Xia
doaj   +1 more source

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