Results 31 to 40 of about 3,514 (186)

Assessment of Photo-Induced Cytotoxic Activity of Cachrys sicula and Cachrys libanotis Enriched-Coumarin Extracts against Human Melanoma Cells

Plants, 2021
Photochemotherapy is one of the most interesting current therapeutic approaches for the treatment of melanoma. Different classes of naturally occurring phytochemicals demonstrated interesting photoactive properties.
Mariangela Marrelli, Maria Rosaria Perri, Valentina Amodeo, Francesca Giordano, Giancarlo A. Statti, Maria Luisa Panno, Filomena Conforti   +6 more
doaj   +1 more source

Imperatorin as a Promising Chemotherapeutic Agent against Human Larynx Cancer and Rhabdomyosarcoma Cells

Molecules, 2020
Naturally occurring coumarins are bioactive compounds widely used in Asian traditional medicine. They have been shown to inhibit proliferation, induce apoptosis, and/or enhance the cytotoxicity of currently used drugs against a variety of cancer cell ...
Aneta Grabarska, Krystyna Skalicka-Woźniak, Michał Kiełbus, Magdalena Dmoszyńska-Graniczka, Paulina Miziak, Justyna Szumiło, Ewa Nowosadzka, Krystyna Kowalczuk, Sherief Khalifa, Jolanta Smok-Kalwat, Janusz Klatka, Krzysztof Kupisz, Krzysztof Polberg, Adolfo Rivero-Müller, Andrzej Stepulak   +14 more
doaj   +1 more source

Cachrys spp. from Southern Italy: Phytochemical Characterization and JAK/STAT Signaling Pathway Inhibition

Plants, 2022
Different phytochemical compounds have been demonstrated to modulate the JAK/STAT signaling pathway. Here, three Cachrys species from Southern Italy were investigated for both the phytochemical profile and the potential anti-inflammatory properties.
Maria Rosaria Perri, Michele Pellegrino, Stefano Aquaro, Fabiola Cavaliere, Carmine Lupia, Dimitar Uzunov, Mariangela Marrelli, Filomena Conforti, Giancarlo Statti   +8 more
doaj   +1 more source

Isolation of furanocoumarins from Pastinaca sativa L. callus culture

Acta Societatis Botanicorum Poloniae, 2014
Four furanocoumarins: bergapten, xanthotoxin, isopimpinellin (linear furanocoumarins) and sphondin (angular furanocoumarin) were isolated for the first time from callus tissues of Pastinaca sativa L.(Apiaceae) cultured in vitro on solid medium.
Halina Ekiert, Wanda Kisiel
doaj   +1 more source

Deverra tortuosa (Desf.) DC from Saudi Arabia as a new source of marmin and furanocoumarins derivatives with α-glucosidase, antibacterial and cytotoxic activities

Heliyon, 2021
Deverra tortuosa (Desf.) DC (Syn. Pituranthos tortusus (Desf.) Benth. & Hook.f.) is a species belonging to the Apiaceae family that is common in the Northern Region of Saudi Arabia.
M. Oueslati, Arbi Guetat, J. Bouajila, A. Alzahrani, Jamith Basha   +4 more
semanticscholar   +1 more source

Imperatorin Influences Depressive-like Behaviors: A Preclinical Study on Behavioral and Neurochemical Sex Differences

Molecules, 2022
Imperatorin, a naturally derived furanocoumarin, exerts promising neuropharmacological properties. Therefore, it might be applicable in the treatment of brain diseases such as depression.
Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Woźniak, Barbara Budzyńska   +6 more
doaj   +1 more source

Phytochemical Profile and In Vitro Antioxidant and Photobiological Properties of Different Extracts from Prangos ferulacea Lindl.

Antioxidants, 2023
Interesting photobiological properties have been demonstrated for some Cachrys species, including C. libanotis L., C. sicula L., and C. pungens Jan. The present study was designed to assess the photocytotoxic activity of Prangos ferulacea Lindl. (synonym
Mariangela Marrelli, Francesca Giordano, Maria Rosaria Perri, Valentina Amodeo, Noemi Baldino, Carmine Lupia, Dimitar Uzunov, Vincenzo Musolino, Filomena Conforti, Maria Luisa Panno   +9 more
doaj   +1 more source

Comparison of the anti-inflammatory activities of furanocoumarins from the roots of Angelica dahurica

Bioactive Compounds in Health and Disease, 2021
Background: The roots of Angelica dahurica Bentham et Hooker filius ex Franchet et Savatier (Apiaceae) have traditionally been used for inflammatory skin diseases. A.
Ryo Okada, Hazuki Abe, T. Okuyama, Yuto Nishidono, Toshinari Ishii, Tatsuki Sato, Saki Shirako, Ken Tanaka, Y. Ikeya, M. Nishizawa   +9 more
semanticscholar   +1 more source

Cytotoxic, Anti-Hemolytic, and Antioxidant Activities of Ruta chalepensis L. (Rutaceae) Extract, Fractions, and Isolated Compounds

Plants, 2023
Ruta chalepensis is an herb used to treat various ailments, and its potential cytotoxic effects on different tumor cell lines have been extensively studied. The present study aimed to evaluate the cytotoxic activity of R.
Joel H. Elizondo-Luévano, Nancy E. Rodríguez-Garza, Aldo F. Bazaldúa-Rodríguez, César I. Romo-Sáenz, Patricia Tamez-Guerra, María J. Verde-Star, Ricardo Gomez-Flores, Ramiro Quintanilla-Licea   +7 more
doaj   +1 more source

Pressurized Liquid Extraction of Coumarins from Fruits of Heracleum leskowii with Application of Solvents with Different Polarity under Increasing Temperature

Molecules, 2012
Coumarins are nowadays an important group of organic compounds from natural sources that are useful in a number of fields. Because they possess different pharmacological properties, finding the proper extraction conditions for their separation from plant
Krystyna Skalicka-Woźniak, Kazimierz Głowniak   +1 more
doaj   +1 more source