Results 11 to 20 of about 488 (118)

The Effect of the N-Oxide Oxygen Atom on the Crystalline and Photophysical Properties of [1,2,5]Oxadiazolo[3,4-d]pyridazines [PDF]

Molecules
A series of novel fluorescent donor–acceptor–donor (D-A-D) dyes containing [1,2,5]oxadiazolo[3,4-d]pyridazine and its 1-oxide as electron-withdrawing groups has been synthesized and thoroughly investigated using X-ray diffraction and molecular ...
Timofey N. Chmovzh, Alisia V. Tsorieva, Vladislav M. Korshunov, Egor D. Kotov, Darina I. Nasyrova, Mikhail E. Minyaev, Nikolay P. Datskevich, Ilya V. Taydakov, Michail N. Elinson, Oleg A. Rakitin   +9 more
doaj   +2 more sources

Anti-breast cancer sinomenine derivatives via mechanisms of apoptosis induction and metastasis reduction [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Sinomenine, a morphinane-type isoquinoline-derived alkaloid, was first isolated from stems and roots of Sinomenium diversifolius (Miq.) in 1920. Later discovery by researchers confirmed various essential biological efficacy sinomenine exerted in vitro ...
Xiang Gao, Baojia Sun, Yonglian Hou, Lilin Liu, Jianan Sun, Fanxing Xu, Dahong Li, Huiming Hua   +7 more
doaj   +2 more sources

Greener Synthesis of Antiproliferative Furoxans via Multicomponent Reactions [PDF]

Molecules, 2022
Prostate and bladder cancers are commonly diagnosed malignancies in men. Several nitric oxide donor compounds with strong antitumor activity have been reported.
Mariana Ingold, Victoria de la Sovera, Rosina Dapueto, Paola Hernández, Williams Porcal, Gloria V. López   +5 more
doaj   +2 more sources

Second generation β-elemene nitric oxide derivatives with reasonable linkers: potential hybrids against malignant brain glioma [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Elemene is a second-line broad-spectrum anti-tumour drug that has been used in China for more than two decades. However, its main anti-tumour ingredient, β-elemene, has disadvantages, including excessive lipophilicity and relatively weak anti-tumour ...
Renren Bai, Junlong Zhu, Ziqiang Bai, Qing Mao, Yingqian Zhang, Zi Hui, Xinyu Luo, Xiang-Yang Ye, Tian Xie   +8 more
doaj   +2 more sources

Synthesis and Characterization of 3,4-Bis[3(2-azidoethoxy)furazan-4-yl]furoxan (DAeTF): A Novel Low-Melting Insensitive Energetic Material [PDF]

Molecules
The synthesis and characterization of low-melting-point insensitive energetic materials are crucial due to their increasing applications in melt–cast explosives.
Yang Wu, Yuezhou Liu, Fulei Gao, Bin Chen, Tingting Lu, Yinglei Wang   +5 more
doaj   +2 more sources

Experiment and Molecular Dynamic Simulation on Interactions between 3,4-Bis(3-nitrofurazan-4-yl) Furoxan (DNTF) and Some Low-Melting-Point Explosives [PDF]

Molecules
3,4-bis(3-nitrofurazan-4-yl) furoxan (DNTF) is an explosive with excellent performance, and the use of DNTF as a high-energy component is of great significance for improving the comprehensive performance of weapons.
Junming Yuan, Runsheng Huang, Jinying Wang, Xiwei Xing, Jing Wang, Tao Han, Qi Yang, Jia Yang   +7 more
doaj   +2 more sources

Tandem diazotization/cyclization approach for the synthesis of a fused 1,2,3-triazinone-furazan/furoxan heterocyclic system [PDF]

Beilstein Journal of Organic Chemistry
A straightforward protocol for the synthesis of a previously unknown [1,2,5]oxadiazolo[3,4-d][1,2,3]triazin-7(6H)-one heterocyclic system was developed. The described approach is based on tandem diazotization/azo coupling reactions of (1,2,5-oxadiazolyl ...
Yuri A. Sidunets, Valeriya G. Melekhina, Leonid L. Fershtat   +2 more
doaj   +2 more sources

Comparative study on the unimolecular decompositions of energetic regioisomers: BFTF-1 and BFTF-2

FirePhysChem, 2023
Regioisomeric energetic materials displayed different properties and performances. Understanding the regioisomerism in energetic materials and how it impacts the properties of energetic materials could provide insights into their improvements and designs.
Jianxin Li, Panpan Heng, Baoshan Wang, Bozhou Wang, Ning Liu, Xiaocong Wang   +5 more
doaj   +1 more source

Unusual reaction of 3,4-bis(3-nitrofurazan-4-yl)furoxan with ammonia, primary amines and hydrazine

Open Chemistry, 2012
Andrei I Stepanov
exaly   +2 more sources

4-Amino-3-(1-{[amino(3-methyl-2-oxido-1,2,5-oxadiazol-4-yl)methylene]hydrazinylidene}ethyl)-1,2,5-oxadiazole 2-Oxide

Molbank, 2022
Functionally substituted 1,2,5-oxadiazole 2-oxides (furoxans) are important pharmaceutical scaffolds used for the preparation of various pharmacologically active substances.
Margarita A. Epishina, Alexander S. Kulikov, Leonid L. Fershtat   +2 more
doaj   +1 more source