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Italian Theatre Today: Not a System, and so Many Transformations
Critical Stages, 2019 Far from being a system, the Italian scene is an agglomeration where historical events, linguistic varieties, places of creation, small and large legislative provisions and artists’ personality shake the theatres and their audiences in an animated chaos.
Roberto Canziani
doaj
Characterization of the role of the RNA-binding protein FUS in the DNA damage response [PDF]
, 2014 FUS/TLS (fused in sarcoma/translocated in liposarcoma), a ubiquitously expressed RNA-binding protein, has been linked to a variety of cellular processes, including RNA metabolism, microRNA biogenesis and DNA repair. However, the precise cellular function
Ruepp, Marc-David
core
Neurobiology of Disease, 2015 Inclusions containing Fused in Sarcoma (FUS) are found in familial and sporadic cases of the incurable progressive motor neuron disease amyotrophic lateral sclerosis and in a common form of dementia, frontotemporal dementia.
Sandra Jäckel +9 more
doaj +1 more source
Characterization of the potential role for RNA-binding protein FUS/TLS in DNA damage response: A quantitative proteomic approach [PDF]
, 2013 FUS/TLS (fused in sarcoma/translocated in liposarcoma) is a ubiquitously expressed RNA-binding protein of the hnRNP family, that has been discovered as fused to transcription factors, through chromosomal translocations, in several human sarcomas and ...
Ruepp, Marc-David
core
PLoS Genetics, 2011 Fused in Sarcoma (FUS) proteinopathy is a feature of frontotemporal lobar dementia (FTLD), and mutation of the fus gene segregates with FTLD and amyotrophic lateral sclerosis (ALS).
Cao Huang +7 more
doaj +1 more source
FUS protein interacts with U7 snRNP and plays a role in replication-dependant histone genes expression [PDF]
, 2013 The U7 small nuclear ribonucleoprotein (U7 snRNP) is an essential factor mediating the unique 3’end processing of non-polyadenylated, replication-dependent histone mRNAs in metazoans. These histone genes expression and processing of their transcripts are
Ruepp, Marc-David
core
FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis [PDF]
, 2022 non
BAGGIO, CHIARA
core
Sequence analysis of FUS-NLS. [PDF]
, 2012 (A). Domain structure of FUS with the C-terminal NLS. The ALS mutations are clustered in the NLS and the mutations studied here are shown in red. (B) Amino acid sequence alignments of FUS-NLS with other PY NLS’s from hnRNP A1, hnRNP D, hnRNP M and TAP ...
Liuqing Yang (128705) +6 more
core +1 more source
Acta Neuropathologica Communications, 2019 Mutations in the FUS gene cause amyotrophic lateral sclerosis (ALS-FUS). Mutant FUS is known to confer cytoplasmic gain of function but its effects in the nucleus are less understood.
Haiyan An +7 more
doaj +1 more source
The FUS protein is associated with mitochondria. [PDF]
, 2016 (A)Highly purified mitochondria were prepared from the control or P525L-FUS-expressing stable HEK cell lines. The mitochondrial purity was confirmed by the detection of mitochondrial CoxIV and the absence of the cytoplasmic proteins such as GAPDH or ...
Marsel Mesulam (2207017) +14 more
core +1 more source