Results 21 to 30 of about 51,631 (223)

FOB microscopy - HeLa P525L GFP-FUS

, 2021
Fluorescence, optical diffraction tomography and Brillouin microscopy data of HeLa P525L GFP-FUS cells under control conditions, after arsenite treatment, and after arsenite treatment and chemical fixation.
Jochen Guck (7429550), Raimund Schlüßler (10339790), Martin Nötzel (8065342), Kyoohyun Kim (9084287)   +3 more
core   +1 more source

Clearance of HR-HPV within one year after focused ultrasound or loop electrosurgical excision procedure in patients with HSIL under 30

International Journal of Hyperthermia, 2022
Objective To compare the clearance rate of high-risk human papillomavirus (HR-HPV) in patients with a high-grade squamous intraepithelial lesion (HSIL) 12 months after focused ultrasound (FUS) or loop electrosurgical excision procedure (LEEP), and ...
Yi Qin, Qing Li, Xunyu Ke, Yan Zhang, Xiaoling Shen, Wenping Wang, Qiuling Shi, Chengzhi Li   +7 more
doaj   +1 more source

Small junction, big problems: Neuromuscular junction pathology in mouse models of amyotrophic lateral sclerosis (ALS)

Journal of Anatomy, Volume 241, Issue 5, Page 1089-1107, November 2022., 2022
Summary of neuromuscular junction (NMJ) changes across ALS mouse models. ALS mouse models show different levels of NMJ pathology depending on gene targets: SOD1, TDP‐43 and FUS models all show initial NMJ dysfunction prior to motor neuron death (arrows), supporting a ‘dying‐back’ theory, while C9orf72 NMJ pathology is less clear. Terminal Schwann cells
Abrar Alhindi, Ines Boehm, Helena Chaytow   +2 more
wiley   +1 more source

A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice

CNS Neuroscience &Therapeutics, Volume 27, Issue 7, Page 765-775, July 2021., 2021
DF402, a fluorine derivative of Dimebon/Latrepirdine, delays the onset and slows the progression of pathology in the transgenic model of ALS‐FUS. An original CatWalk analysis protocol allowing detection of gait changes in FUS transgenic mice long before manifestation of clinical signs reveals effects of DF402 on their gait at early pre‐symptomatic ...
Kirill Chaprov, Alexander Rezvykh, Sergei Funikov, Tamara A. Ivanova, Ekaterina A. Lysikova, Alexei V. Deykin, Michail S. Kukharsky, Alexey Yu. Aksinenko, Sergey O. Bachurin, Natalia Ninkina, Vladimir L. Buchman   +10 more
wiley   +1 more source

Clinical efficacy and mechanism for focused ultrasound (FUS) in the management of cervical intraepithelial neoplasia 1 (CIN1)

International Journal of Hyperthermia, 2020
Objective This study was aimed at investigating the clinical efficacy and studying the possible mechanism of FUS applications to treat cervical intraepithelial neoplasia 1 (CIN1).
Zhenhua Fu, Yijin Fan, Can Wu, Ping Yan, Yibi Ye, Huan Yang, Chengzhi Li   +6 more
doaj   +1 more source

Sobel edge detection for quantifying the effectiveness of focused ultrasound thalamotomy for tremor relief

Current Directions in Biomedical Engineering, 2023
Focused ultrasound on the thalamus is employed to relieve tremor in movement disorders. The treatment efficacy is currently assessed by subjective observation of patient tremor during hand movements.
Aharonson Vered, Postema Michiel, Gebbie Robyn, Van Der Merwe Jesse, Schlesinger Ilana   +4 more
doaj   +1 more source

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA [PDF]

, 2012
Mutations in the RNA binding protein FUS cause amyotrophic lateral sclerosis (ALS), a fatal adult motor neuron disease. Decreased expression of SMN causes the fatal childhood motor neuron disorder spinal muscular atrophy (SMA).
Das, Rita, Maniatis, Tom, Sharma, A, Yan, Biao, Tapia, JC, Gygi, Steve P., Monica A. Carrasco, Shneider, NA, Nishimura, AL, Chen, Shi, Yu, Yong, Sharma, Aarti, Yan, B, Gygi, SP, Christopher E. Shaw, Yamazaki, T, Steve P. Gygi, Siddharthan Chandran, Reed, Robin, Yu, Y, Aarti Sharma, Reed, R, Yong Yu, Rita Das, Das, R, Carrasco, Monica A., Zhai, Bo, Shneider, Neil A., Chen, S, Juan C. Tapia, Tapia, Juan C., Agnes Lumi Nishimura, Lalancette-Hebert, Melanie, Haertlein, TC, Tom Maniatis, Lalancette-Hebert, M, Biao Yan, Carrasco, MA, Neil A. Shneider, Yamazaki, Tomohiro, Nishimura, Agnes Lumi, Sullivan, G, Maniatis, T, Shaw, Christopher E., Shi Chen, Zhai, B, Melanie Lalancette-Hebert, Sullivan, Gareth, Tyler C. Haertlein, Shaw, CE, Chandran, S, Haertlein, Tyler C., Tomohiro Yamazaki, Gareth Sullivan, Robin Reed, Bo Zhai, Chandran, Siddharthan   +56 more
core   +1 more source

Determination of the Cavitation Pressure Threshold in Focused Ultrasound Wave Fields applied to Sonosensitive, Biocompatible Nanoparticles for Drug Delivery Applications

Current Directions in Biomedical Engineering, 2020
Employing sonosensitive nanoparticles as carriers of active pharmaceutical ingredients emerges in ultrasonic Drug Delivery. Drug release can be initiated by focused ultrasound via the effect of inertial cavitation in certain target areas of particle ...
George Benedikt, Lehner Markus, Fink Michael, Rupitsch Stefan J., Ermert Helmut, Hiltl Pia T., Savšek Ula, Lee Geoffrey   +7 more
doaj   +1 more source

A Genetic Screen for Human Genes Suppressing FUS Induced Toxicity in Yeast

G3: Genes, Genomes, Genetics, 2020
FUS is a nucleic acid binding protein that, when mutated, cause a subset of familial amyotrophic lateral sclerosis (ALS). Expression of FUS in yeast recapitulates several pathological features of the disease-causing mutant proteins, including nuclear to ...
Elliott Hayden, Shuzhen Chen, Abagail Chumley, Chenyi Xia, Quan Zhong, Shulin Ju   +5 more
doaj   +1 more source

Le tourisme jurassien [PDF]

Geographica Helvetica
No abstract available.
P. Rumley
doaj   +1 more source