Results 111 to 120 of about 1,288,108 (273)
Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains [PDF]
, 2016 The initial, nanometer-sized connection between the plasma membrane and a hormone- or neurotransmitter-filled vesicle –the fusion pore– can flicker open and closed repeatedly before dilating or resealing irreversibly.
Vennekate, W +13 more
core +1 more source
Retrovirology, 2018 Background The native pre-fusion structure of gp120/gp41 complex of human immunodeficiency virus type 1 was recently revealed. In the model, the helices of gp41 (α6, α7, α8, and α9) form a four-helix collar underneath trimeric gp120.
Dehua Liu +8 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Pixel Level Image Fusion using Fuzzylet Fusion Algorithm [PDF]
, 2013 Image fusion algorithms based on SWT (Stationary Wavelet Transform) and fuzzy logic were developed and demonstrated. It was observed that fusion using SWT with higher levels of decomposition provides better fusion results. Similarly, Fuzzy image fusion
Bindu, Elias, Naidu, VPS, Swathi, Nair
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Multi-resolution, multi-sensor image fusion: general fusion framework [PDF]
, 2011 Multi-resolution image fusion also known as pansharpening aims to include spatial information from a high resolution image, e.g. panchromatic or Synthetic Aperture Radar (SAR) image, into a low resolution image, e.g.
Palubinskas, Gintautas +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Surgical Subtask Automation for Intraluminal Procedures using Deep Reinforcement Learning [PDF]
, 2023 Intraluminal procedures have opened up a new sub-field of minimally invasive surgery that use flexible instruments to navigate through complex luminal structures of the body, resulting in reduced invasiveness and improved patient benefits.
Ameya Pore
core
Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State
Cell Reports, 2017 Summary: One of the key research areas surrounding HIV-1 concerns the regulation of the fusion event that occurs between the virus particle and the host cell during entry.
Daniel M. Jones +8 more
doaj +1 more source