Results 131 to 140 of about 1,811,201 (303)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structure formation in binary mixtures of lipids and detergents: Self-assembly and vesicle division

, 2012
Self-assembly dynamics in binary surfactant mixtures and structure changes of lipid vesicles induced by detergent solution are studied using coarse-grained molecular simulations.
Noguchi, Hiroshi
core   +1 more source

Oxygen semipermeable solid oxide membrane composites prepared by electrochemical vapor deposition [PDF]

, 1992
Ceramic membrane composites consisting of a coarse porous -alumina or two-layer porous alumina membrane support and an oxygen semipermeable gas tight thin (0.2–5 μm) yttria stabilized zirconia (YSZ) film are prepared by the electrochemical vapor ...
Brinkman, H.W., Burggraaf, A.J., Lin, Y.S., Vries, K.J. de   +3 more
core   +3 more sources

Detecting keyhole pore defects and monitoring process signatures during laser powder bed fusion: A correlation between in situ pyrometry and ex situ X-ray radiography

, 2020
Creation of pores and defects during laser powder bed fusion (LPBF) can lead to poor mechanical properties and thus must be minimized. Post-build inspection is required to ensure the printed parts contain acceptably low defect concentrations.
J. Forien, N. Calta, P. DePond, G. Guss, T. Roehling, M. Matthews   +5 more
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Aging differentially affects multiple aspects of vesicle fusion kinetics.

PLoS ONE, 2011
How fusion pore formation during exocytosis affects the subsequent release of vesicle contents remains incompletely understood. It is unclear if the amount released per vesicle is dependent upon the nature of the developing fusion pore and whether full ...
Mark P Zanin, Lucy Phillips, Kimberly D Mackenzie, Damien J Keating   +3 more
doaj   +1 more source

Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis [PDF]

J Cell Biol, 2023
Biton T, Scher N, Carmon S, Elbaz-Alon Y, Schejter ED, Shilo B, Avinoam O.   +6 more
europepmc   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Pores in Bilayer Membranes of Amphiphilic Molecules: Coarse-Grained Molecular Dynamics Simulations Compared with Simple Mesoscopic Models

, 2004
We investigate pores in fluid membranes by molecular dynamics simulations of an amphiphile-solvent mixture, using a molecular coarse-grained model. The amphiphilic membranes self-assemble into a lamellar stack of amphiphilic bilayers separated by solvent
Bouligand Y., Brodatzki U., C. Loison, Constantin D., F. Schmid, Hed G., Holmes M., Khanta M., Lawaczeck R., Lister J. D., Loison C., M. Mareschal, May S., Mecke K. R., Milchielsen K., Safran S. A., Sung W., Zahn D.   +17 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source