Results 241 to 250 of about 1,121,449 (385)

Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2. [PDF]

Emerg Microbes Infect
Chan P, Ye ZW, Zhao W, Ong CP, Sun XY, Cheung PH, Jin DY.   +6 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Transgenic soybean expressing Cry1Ab-Vip3A fusion protein confers broad-spectrum resistance to lepidopteran pest. [PDF]

Plant Cell Rep
Pan Z, Zhu Y, Lin C, Tang M, Shen Z, Zheng T.   +5 more
europepmc   +1 more source

Parasitic nematode vaccine for human and animal protection fusion protein expression

, 1989

openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Generation and characterization of OX40-ligand fusion protein that agonizes OX40 on T-Lymphocytes. [PDF]

Front Immunol
Sato A, Nagai H, Suzuki A, Ito A, Matsuyama S, Shibui N, Morita M, Hikosaka-Kuniishi M, Ishii N, So T.   +9 more
europepmc   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Novel fusion protein REA induces robust prime protection against tuberculosis in mice. [PDF]

NPJ Vaccines
Gurmessa SK, Choi HG, Back YW, Jiang Z, Pham TA, Choi S, Kim HJ.   +6 more
europepmc   +1 more source

A bacterial peptide acting as a plant nuclear targeting signal: the amino-terminal portion of Agrobacterium VirD2 protein directs a beta-galactosidase fusion protein into tobacco nuclei.

, 1990
Alfredo Herrera‐Estrella, Marc Van Montagu, K Wang   +2 more
openalex   +1 more source

Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein [PDF]

, 1994
Alan Rein, Jane Mirro, Jacy Haynes, S M Ernst, Kunio Nagashima   +4 more
openalex   +1 more source