Results 101 to 110 of about 2,644 (175)
, 2013 FXR1-WT (▪) and FXR1-KO (□) macrophages (50×106 cells) were untreated or pre-treated with 4HPR (0.625 µM) for 21 h and then unstimulated or stimulated for 3 h with LPS (50 ng/ml). Cells were harvested and resuspended in BHA solution.
Juan B. De Sanctis (429776) +5 more
core +1 more source
Circadian Regulation of the RNA-binding Protein Fxr1 and its Role in Regulating Core Clock Genes [PDF]
, 2022 The fragile X autosomal homolog 1 (Fxr1) is an RNA-binding protein that controls mRNA translation and has been associated to mood regulation, schizophrenia, and bipolar disorders.
Soares Silva, Tiago
core
, 2013 Results are expressed as mean ± SEM of TNF mRNA relative expression level using FXR1-WT medium as calibrator. The p values were calculated using unpaired t-test.ap values refer to Medium versus 4HPR or LPS versus LPS & 4HPR group.bp values refer to FXR1 ...
Juan B. De Sanctis (429776) +5 more
core +1 more source
FXR1 modulates the expression of a subset of miRNAs in oral cancer cells.
, 2020 (A) Volcano plot of differential miRNA expression in UMSCC74B cells in the absence of FXR1. Red: up-regulated and green: down-regulated miRNAs in the absence of FXR1.
Mrinmoyee Majumder (3110004) +1 more
core +1 more source
, 2019 Transfection efficiency of FXR1, MIR17HG, miR-346, miR-425-5p, TAL1 and DEC1.
Chunqing Yang (6271727) +12 more
core +1 more source
Antagonism of stress granules is key to SARS-CoV-2 infection and pathogenesis
Journal of VirologyViruses must subvert host responses to facilitate successful infection. While most antiviral responses are associated with interferons, stress granules (SGs) are another barrier to viral infection by inducing translation arrest.
R. Elias Alvarado +17 more
doaj +1 more source
Rare case of congenital myopathy associated with the FXR1 gene
Arquivos de Neuro-Psiquiatria, 2023 Isadora Cavalcante Olímpio de Melo +7 more
openaire +1 more source
4HPR reduces excessive phosphorylation of MAP kinase ERK1/2 in FXR1-KO macrophages.
, 2013 FXR1-WT (▪) and FXR1-KO (□) macrophage cell lines (1×106 cells) were unstimulated (medium) or stimulated for 30 min with LPS (50 ng/ml). Both macrophage cell lines were also treated with 4HPR (0.62 µM) under LPS stimulation conditions.
Juan B. De Sanctis (429776) +5 more
core +1 more source
, 2010 Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of inflammation in host defence against infection and in autoimmune disease. Its production is controlled post-transcriptionally by multiple RNA-binding proteins that interact with the TNF-alpha ...
Andrew D. Dick +5 more
core +1 more source
Hypertension affects about half of the US population. Vascular changes that occur in hypertension may be in part due to changes in vascular smooth muscle cell (VSMC) cytoskeletal dynamics and actomyosin interactions.
Amanda Peluzzo +4 more
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