Results 111 to 120 of about 1,143 (122)

PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells. [PDF]

open access: yesNucleic Acids Res
Vijayakumar A   +10 more
europepmc   +1 more source

5-Methylcytosine-Modified circRNA-CCNL2 Regulates Vascular Remdeling in Hypoxic Pulmonary Hypertension Through Binding to FXR2

International Journal of Biological Macromolecules
Pulmonary hypertension (PH) is a malignant cardiovascular disease with a complex etiology. 5-Methylcytosine (m5C) is a post-transcriptional RNA modification identified in both stable and highly abundant RNAs, with a lower frequency of occurrence in circular RNAs (circRNAs).
June Bai, Hanliang Sun, Xinyue Song
exaly   +3 more sources

Expression of Three Zebrafish Orthologs of Human FMR1-Related Genes and Their Phylogenetic Relationships

open access: yesDevelopment Genes and Evolution, 2004
The original publication can be found at www.springerlink.comThe human fragile X mental retardation syndrome is caused by expansions of a CGG repeat in the FMR1 gene. FXR1 and FXR2 are autosomal paralogs of FMR1.
Michael Lardelli, Robert Ian Richards
exaly   +2 more sources

Loss of FXR1 and FXR2 promotes accumulation of TDP-43 in aging-related stress granules

Abstract Cytoplasmic mislocalization and aggregation of the RNA-binding protein TDP-43 in vulnerable neurons may accompany the primary neuropathology of various neurodegenerative diseases, or represent the hallmark of others, such as amyotrophic lateral sclerosis.
Sonja Menge   +4 more
openaire   +1 more source

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