Results 121 to 130 of about 1,075 (130)

5-Methylcytosine-modified circRNA-CCNL2 regulates vascular remdeling in hypoxic pulmonary hypertension through binding to FXR2

International Journal of Biological Macromolecules
Pulmonary hypertension (PH) is a malignant cardiovascular disease with a complex etiology. 5-Methylcytosine (m5C) is a post-transcriptional RNA modification identified in both stable and highly abundant RNAs, with a lower frequency of occurrence in circular RNAs (circRNAs).
Hanliang Sun, June Bai
exaly   +3 more sources

Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships

open access: yesDevelopment Genes and Evolution, 2004
The original publication can be found at www.springerlink.comThe human fragile X mental retardation syndrome is caused by expansions of a CGG repeat in the FMR1 gene. FXR1 and FXR2 are autosomal paralogs of FMR1.
Ben Tucker   +2 more
exaly   +2 more sources

Loss of FXR1 and FXR2 promotes accumulation of TDP-43 in aging-related stress granules

Abstract Cytoplasmic mislocalization and aggregation of the RNA-binding protein TDP-43 in vulnerable neurons may accompany the primary neuropathology of various neurodegenerative diseases, or represent the hallmark of others, such as amyotrophic lateral sclerosis.
Sonja Menge   +4 more
openaire   +1 more source

Delayed Development of Dendritic Spines in Fxr2 Knockout Mouse

The Open Neuroscience Journal, 2021
Jinbo Deng   +2 more
exaly  

NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2)

Biochemical Journal, 2006
Karen Usdin, Usdin Karen
exaly  

Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer

Critical Reviews in Biochemistry and Molecular Biology, 2020
Mrinmoyee Majumder   +1 more
exaly  

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