Results 181 to 190 of about 18,199,019 (306)

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a. [PDF]

Int J Mol Med
Vu LAT, Gerhards J, Maerz LD, Burkhalter MD, Philipp M.   +4 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

G-protein activation of the dark-state conformation of the visual G protein-coupled receptor rhodopsin by releasing critical structural constraints. [PDF]

Commun Biol
Ramon E, Kirchberg K, Jiménez-Rosés M, Balke J, Kim TY, Cordomí A, Alexiev U, Garriga P.   +7 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Adhesion G protein-coupled receptors. [PDF]

Pharmacol Rev
Langenhan T, Anderson GR, Araç D, Aust G, Avila-Zozaya M, Bagger SM, Barth P, Berndt S, Blacklow SC, Blanco-Redondo B, Boucard AA, Bridges JP, Brodmerkel LS, Caron KM, Chung YK, Dates AN, de Araujo Farias V, Del Toro D, Duman JG, Engel FB, Favara DM, Formstone CJ, Fu C, Garcia De Las Bayonas A, Georgiadi A, Gloriam DE, Hall RA, Hamann J, Hildebrand PW, Hsiao CC, Huang BX, Javitch JA, Kim HY, Kittel RJ, Kleinau G, Leduc R, Liebscher I, Lin HH, Linnert J, Ludwig MG, Martinelli DC, Mathiasen S, Matúš D, Melkumyan M, Moreno-Salinas AL, Mulder J, Nash MA, Pal K, Pederick DT, Perry-Hauser NA, Piao X, Ping YQ, Placantonakis DG, Pohl F, Prömel S, Rosenkilde MM, Sabbagh L, Sando RC, Scheerer P, Schöneberg T, Seiradake E, Selcho M, Seufert F, Singh AK, Skiniotis G, Spiess K, Sträter N, Strutt D, Südhof TC, Sun J, Tall GG, Thor D, Tilley DG, Tolias KF, Vallon M, Van Meir EG, Vanhollebeke B, Wiggin GR, Wolfrum U, Yan J, Zaidman NA, Zou Y, Scholz N.   +82 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A widespread actinobacterial G protein system regulates production of specialized metabolites in <i>Streptomyces coelicolor</i>. [PDF]

mSphere
Cantu Morin LM, Vunnum A, Binns S, Traxler MF.   +3 more
europepmc   +1 more source

Interaction of G protein with G protein activating peptides

Seibutsu Butsuri, 2003
T. Morikawa, T. Ishii, A. Arai, T. Kohno, K. Sato, Y. Kato, M. Tanokura, K. Wakamatsu   +7 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

β-Arrestin condensates regulate G-protein-coupled receptor function. [PDF]

Nature
Anderson PJ, Xiao P, Zhong YN, Kaakati AN, Alfonso-DeSouza J, Patino A, Ahn A, Jassal C, Zhang T, Zhang C, Yu K, Qi L, Ding W, Liu S, Pani B, Krishnan A, Chen O, Strawn J, Snyder JC, Sun JP, Rajagopal S.   +20 more
europepmc   +1 more source