Results 1 to 10 of about 10,638 (129)
ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs [PDF]
ADP-ribosylation factors (ARFs) are GTP-binding proteins that were discovered in the early 1980s, shortly after heterotrimeric GTP-binding proteins (G proteins) and nearly simultaneously with RAS.
Rachel E. Turn +5 more
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Roles of Heterotrimeric GTP-Binding Proteins in the Progression of Heart Failure
.: Heart failure is a major cause of death in developed countries, and the development of an epoch-making cure is desired from the viewpoint for improving the quality of life and reducing the medical cost of the patient.
Motohiro Nishida
doaj +4 more sources
Heterotrimeric G Protein–RasGAP Coupling Drives Adaptation During Chemotaxis [PDF]
Chemotaxis enables eukaryotic cells to detect and migrate along extracellular chemoattractant gradients spanning several orders of magnitude. This remarkable dynamic range relies on adaptation, a process that allows cells to reset their signaling ...
Xuehua Xu +4 more
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Heterotrimeric and unconventional GTP binding proteins in plant cell signaling. [PDF]
Signal-transducing GTPases in plants include small G proteins, heterotrimeric G proteins, and, potentially, several unique types of GTP binding proteins that are not members of either of the aforementioned classes.
Sarah M. Assmann
exaly +3 more sources
Genome-Wide Identification of the Heterotrimeric G-Protein Gene Family and Its Transcriptional Response to Salt Stress in Foxtail Millet [PDF]
Heterotrimeric GTP-binding proteins, commonly known as G proteins, act as core molecular switches in plant signal transduction, governing multiple biological processes including plant growth, development, phytohormone signaling, and abiotic stress ...
Xiuyan Cui +9 more
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Nucleotide exchange-dependent and nucleotide exchange-independent functions of plant heterotrimeric GTP-binding proteins. [PDF]
G protein α subunits in Arabidopsis can function independently of guanine nucleotide exchange.
Maruta N +5 more
europepmc +7 more sources
Characterization of the GTPγS release function of a G protein-coupled receptor [PDF]
G protein-coupled receptor (GPCR) signaling is one of the most ubiquitous and sensitive forms of cell surface reception. GPCRs stabilize the nucleotide-free state of heterotrimeric guanine-nucleotide binding proteins (G proteins); however, this state is ...
Laura M. Bohn, Edward L. Stahl
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Heterotrimeric G proteins are involved in hormonal signal transduction across the plasma membrane. Recent evidence suggests that they have a role in vesicular protein transport as well. Biochemical probes that interfere with the classical G protein cycle have been applied to the field of intracellular membrane transport to study their mechanism of ...
J B Helms
exaly +4 more sources
Guanine nucleotide-binding (G) proteins, namely, phosphate-binding (P) loop GTPases, play a critical role in life processes among different species. Based on the structural characteristics, G proteins can be divided into heterotrimeric G proteins, small ...
Maozhen Luo +7 more
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Interaction of Prokineticin Receptors with Accessory Proteins
G protein-coupled receptors (GPCRs) are transmembrane proteins that mediate the intracellular pathway of signals not only through heterotrimeric GTP-binding proteins (G proteins) but also through their associations with a variety of additional partner ...
Roberta Lattanzi, Rossella Miele
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