Results 21 to 30 of about 2,645,999 (191)

Role of heterotrimeric Gα proteins in maize development and enhancement of agronomic traits. [PDF]

open access: yesPLoS Genetics, 2018
Plant shoot systems derive from the shoot apical meristems (SAMs), pools of stems cells that are regulated by a feedback between the WUSCHEL (WUS) homeobox protein and CLAVATA (CLV) peptides and receptors.
Qingyu Wu   +3 more
doaj   +1 more source

The association of heterotrimeric GTP-binding protein (Go) with microtubules

open access: yesJournal of Biomedical Science, 2001
The heterotrimeric GTP-binding regulatory proteins (G proteins) play an important role in the regulation of membrane signal transduction. Recently, we identified the association of Go protein with mitotic spindles. Here we have investigated the relationship between Go protein and microtubules. We used temperature-dependent reversible assembly and taxol
H C, Wu, C Y, Chiu, P H, Huang, C T, Lin
openaire   +2 more sources

Control of striatal signaling by G protein regulators

open access: yesFrontiers in Neuroanatomy, 2011
Signaling via heterotrimeric G proteins plays a crucial role in modulating the responses of striatal neurons that ultimately shape core behaviors mediated by the basal ganglia circuitry, such as reward valuation, habit formation and movement coordination.
Keqiang eXie, Kirill eMartemyanov
doaj   +1 more source

Role of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction. [PDF]

open access: yesPLoS ONE, 2015
GPCRs catalyze GDP/GTP exchange in the α-subunit of heterotrimeric G proteins (Gαßγ) through displacement of the Gα C-terminal α5 helix, which directly connects the interface of the active receptor (R*) to the nucleotide binding pocket of G.
Alexander S Rose   +5 more
doaj   +1 more source

The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1. [PDF]

open access: yesPLoS ONE, 2011
Heterotrimeric G protein α subunits are activated upon exchange of GDP for GTP at the nucleotide binding site of Gα, catalyzed by guanine nucleotide exchange factors (GEFs). In addition to transmembrane G protein-coupled receptors (GPCRs), which act on G
Celestine J Thomas   +7 more
doaj   +1 more source

RGG1, Involved in the Cytokinin Regulatory Pathway, Controls Grain Size in Rice

open access: yesRice, 2020
Heterotrimeric GTP binding proteins (G proteins) and cytokinin play important roles in regulating plant growth and development. However, little is known about the mechanism by which they coordinate the regulation of grain size in rice.
Yajun Tao   +12 more
doaj   +1 more source

The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]

open access: yes, 2002
Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Soll, J.   +5 more
core   +1 more source

Current Topics in Heterotrimeric GTP-binding Proteins. Heterotrimeric G proteins and ion channels.

open access: yesFolia Pharmacologica Japonica, 1994
Direct G protein regulation of ion channels is one of the major mechanisms of the functional regulation of excitable cells by hormones and neurotransmitters. Recent extensive studies indicate that a number of channels are directly regulated by G proteins.
YAMADA, Mitsuhiko, KURACHI, Yoshihisa
openaire   +3 more sources

Novel Mutant Alleles Reveal a Role of the Extra-Large G Protein in Rice Grain Filling, Panicle Architecture, Plant Growth, and Disease Resistance

open access: yesFrontiers in Plant Science, 2022
Plant growth and grain filling are the key agronomical traits for grain weight and yield of rice. The continuous improvement in rice yield is required for a future sustainable global economy and food security.
Akshaya K. Biswal   +10 more
doaj   +1 more source

Comparative structural dynamic analysis of GTPases.

open access: yesPLoS Computational Biology, 2018
GTPases regulate a multitude of essential cellular processes ranging from movement and division to differentiation and neuronal activity. These ubiquitous enzymes operate by hydrolyzing GTP to GDP with associated conformational changes that modulate ...
Hongyang Li, Xin-Qiu Yao, Barry J Grant
doaj   +1 more source

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