Results 201 to 210 of about 3,592,863 (264)

Loss of erythrocyte arginase-1 impairs vasorelaxation due to endothelial GSNOR overexpression and denitrosylation of G protein subunits. [PDF]

open access: yesRedox Biol
Gogiraju R   +16 more
europepmc   +1 more source

Anti-Inflammatory Potential of Novel Tethered Agonists of the Adhesion G Protein-Coupled Receptor F5. [PDF]

open access: yesInt J Mol Sci
Wnorowski A   +8 more
europepmc   +1 more source

G proteins

Trends in Biochemical Sciences, 1992
The family of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) serves an essential role in transducing receptor-generated signals across the plasma membrane. Recent findings reveal unexpected functional roles for individual G protein subunits.
J R, Hepler, A G, Gilman
openaire   +4 more sources

G protein antagonists

Trends in Pharmacological Sciences, 1999
Heterotrimeric G proteins couple membrane-bound heptahelical receptors to their cellular effector systems (ion channels or enzymes generating a second messenger). In current pharmacotherapy, the input to G protein-regulated signalling is typically manipulated by targeting the receptor with appropriate agonists or antagonists and, to a lesser extent, by
M, Freissmuth   +3 more
openaire   +2 more sources

The role of G protein conformation in receptor–G protein selectivity

Nature Chemical Biology, 2023
G protein-coupled receptors (GPCRs) selectively activate at least one of the four families of heterotrimeric G proteins, but the mechanism of coupling selectivity remains unclear. Structural studies emphasize structural complementarity of GPCRs and nucleotide-free G proteins, but selectivity is likely to be determined by transient intermediate-state ...
Wonjo Jang   +4 more
openaire   +2 more sources

G Proteins and Phototransduction

Annual Review of Physiology, 2002
▪ Abstract  Phototransduction is the process by which a photon of light captured by a molecule of visual pigment generates an electrical response in a photoreceptor cell. Vertebrate rod phototransduction is one of the best-studied G protein signaling pathways. In this pathway the photoreceptor-specific G protein, transducin, mediates between the visual
Vadim Y, Arshavsky   +2 more
openaire   +2 more sources

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