The role of inhibitory G proteins and regulators of G protein signalling in the in-vivo control of heart rate and predisposition to cardiac arrhythmias [PDF]
Frontiers in Physiology, 2012 Inhibitory heterotrimeric G-proteins and the control of heart rate.The activation of cell signalling pathways involving inhibitory heterotrimeric G-proteins acts to slow the heart rate via modulation of ion channels.
Richard eAng +2 more
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Medicine Science, 2022 Rabies is a viral disease caused by the rabies virus (Lyssavirus) that affects the central nervous system, ultimately leading to death and brain disease. Rabies usually transmitted through a bite among domestic dogs and wild carnivorous animals.
Gulshan Mammadova +6 more
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BSA nanoparticles loaded with IONPs for biomedical applications: fabrication optimization, physicochemical characterization and biocompatibility evaluation [PDF]
Nanomedicine Journal, 2019 Objective(s): Cancer diagnosis in its early stages of progress, can enhance the efficiency of treatment utilizing conventional therapy methods. Non-biocompatibility of iron oxide nanoparticles (IONPs) has made a big challenge against their usage as a ...
Parvin Najafi, Hasan Kouchakzadeh
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Auriculocondylar syndrome 2 results from the dominant-negative action of PLCB4 variants
Disease Models & Mechanisms, 2022 Auriculocondylar syndrome 2 (ARCND2) is a rare autosomal dominant craniofacial malformation syndrome linked to multiple genetic variants in the coding sequence of phospholipase C β4 (PLCB4). PLCB4 is a direct signaling effector of the endothelin receptor
Stanley M. Kanai +9 more
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Structure-Guided Designing and Evaluation of Peptides Targeting Bacterial Transcription
Frontiers in Bioengineering and Biotechnology, 2020 The mycobacterial RNA polymerase (RNAP) is an essential and validated drug target for developing antibacterial drugs. The β-subunit of Mycobacterium tuberculosis (Mtb) RNAP (RpoB) interacts with an essential and global transcription factor, CarD, and ...
Gundeep Kaur +4 more
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The Evolution of Intein-Based Affinity Methods as Reflected in 30 years of Patent History
Frontiers in Molecular Biosciences, 2022 Self-cleaving affinity tags, based on engineered intein protein domains, have been touted as a universal single step purification platform for tagless non-mAb proteins.
Sai Vivek Prabhala +3 more
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eLife, 2020 The >800 human G protein–coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets.
Eric M Jones +12 more
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Nutritional characteristics of selected insects in Uganda for use as alternative protein sources in food and feed [PDF]
, 2020 Open Access Journal; Published online: 18 Dec 2019Insects are potential ingredients for animal feed and human food. Their suitability may be influenced by species and nutritional value.
Bbosa, T. +4 more
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Plant Signaling & Behavior, 2022 Guanine nucleotide-binding (G) proteins, namely, phosphate-binding (P) loop GTPases, play a critical role in life processes among different species. Based on the structural characteristics, G proteins can be divided into heterotrimeric G proteins, small ...
Maozhen Luo +7 more
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Effects of dietary protein and fiber at breakfast on appetite, ad libitum energy intake at lunch, and neural responses to visual food stimuli in overweight adults [PDF]
, 2016 Increasing either protein or fiber at mealtimes has relatively modest effects on ingestive behavior. Whether protein and fiber have additive or interactive effects on ingestive behavior is not known.
Amankwaah, Akua F. +10 more
core +3 more sources