Results 261 to 270 of about 43,333,653 (285)

Cholinergic G protein‐coupled bile acid receptor 1 (TGR5/GPBA) in the medial septal orchestrates adult hippocampal neurogenesis and cognition in Alzheimer's disease mice

British Journal of Pharmacology
Background and PurposeThe pathological role of the bile acid receptor TGR5/GPBA in Alzheimer's disease (AD) is not fully understood. We investigated the pharmacological effects and mechanisms of TGR5 in AD model mice.Experimental ApproachTGR5 expression was assessed in AD mice using immunofluorescence and immunoblotting.
Rui‐Zhe Nie, Qi‐Lu Zhang, Xin‐Ru Tan, Shan‐Shan Hu, Xin‐Ting Zhou, Wei‐Kai Jiang, Bo‐Wei Guo, Xian Cao, Dan‐Hua Yuan, Yan Long, Hao Hong, Su‐Su Tang   +11 more
openaire   +2 more sources

A Pan-Cancer Analysis of the Oncogenic Role of G Protein-Coupled Bile Acid Receptor 1(GPBAR1) in Human Tumors

SSRN Electronic Journal, 2021
Zhiyuan Guan, Xiao Jin, Shengfu Liu, Zhong Wu, Ruijun Cong, Zhiqiang Guan, Xu Li, Kun Tao   +7 more
openaire   +1 more source

Type-2 diabets and G-protein coupled bile acid receptor 1

2022
openaire   +1 more source

Discovery of novel cholic acid derivatives as highly potent agonists for G protein-coupled bile acid receptor

Bioorganic Chemistry, 2022
Xin Chen, Jingjing Sun, Shuai Zhao
exaly  

Deoxyschizandrin ameliorates obesity and non-alcoholic fatty liver disease: Involvement of dual Farnesyl X receptor/G protein-coupled bile acid receptor 1 activation and leptin sensitization

Phytotherapy Research, 2023
Shengjie Fan, Ming Gu, Yaru Feng
exaly  

Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa

Neurogastroenterology and Motility, 2020
Helen M. Cox, Thue W Schwartz, Iain R Tough   +2 more
exaly  

Faculty Opinions recommendation of Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2014
Gianfranco Alpini, Anastasia Renzi
openaire   +1 more source

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Zeitschrift für Gastroenterologie, 2015
C Chintalapati, C Wöhler, C Ehlting, J Bode, D Häussinger, V Keitel   +5 more
openaire   +1 more source

Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease

Journal of the American Heart Association, 2023
Mariarosaria Bucci, Cristina Di Giorgio, Rosalinda Roselli   +2 more
exaly  

Tu1621 Farnesoid X Receptor (FXR) Regulates Intestinal G Protein-Coupled Bile Acid Receptor 1 and Glucagon-Like Peptide 1 Secretion

Gastroenterology, 2016
Preeti Pathak, Shannon Boehme, John Y. Chiang   +2 more
openaire   +1 more source